Congenital nephrotic syndrome is a term used to describe a condition in babies who develop severe proteinuria and hypoalbuminaemia within their first three months of life. They generally have oedema and ascites from birth which, because of increased intra-abdominal pressure, can result in an umbilical hernia. The report presents a five-month old infant with congenital nephrotic syndrome who had...

shwaehman syndrome, next to cystic fibrosis, is the second cause of congenita! exocrine pancreatic insufficiency in children. it appears as steatorrhea, recurrent infections and hematologic abnormalities such as neutropenia, skeletal dysplasia and short stature. in this study, we reviewed 3 patients' histories. all of them showed cellular chemotaxic defect. one of them had been affected by neph...

Keywords Disease name and synonyms Definition Incidence Clinical description Histology Treatment Etiology Antenatal diagnosis References Abstract The congenital nephrotic syndrome of the Finnish type is a hereditary disease with autosomal recessive inheritance. The gene frequency is approximately 1/200 in Finland. The disease is caused by mutations in the gene for nephrin, which is a key compon...

INTRODUCTION Identification of the NPHS1 gene, which encodes nephrin, was followed by many studies demonstrating its mutation as a frequent cause of congenital nephrotic syndrome (CNS). While this gene is found in 98% of Finnish children with this syndrome, non-Finnish cases have lower level of incidence ranging from 39 to 80%. CASE REPORT This report describes the clinical presentation of a ...

Background: Nephrotic syndrome and type 1 diabetes mellitus are two common chronic conditions in children. Co-existence of these conditions is an extremely rare finding. Case presentation: This report presents a 6-year-old boy who was diagnosed with nephrotic syndrome five years ago and type 1 diabetes mellitus in infancy. Renal biopsy showed membranous glomerulonephritis, which is a rare h...

Background Nephrotic syndrome (NS) characterized by a large amounts of protein into urine and a set of indications that include: protein in urine, low blood protein levels, high cholesterol levels, high triglyceride levels, and swelling. Therefore, aim of this study was to investigate the relationship between prognosis of nephrotic syndrome and blood biomarkers level in children of Arak city, I...