Syrenomelia sequence is a rare (incidence of 1: 60000 births) [1,2] lethal pattern of congenital anomalies characterized by a number of hallmark skeletal anomalies including fusion of the lower extremities or a single lower limb, bilateral renal agenesis or dysgenesis with absent or hypoplastic renal arteries, oligohydramnios and the presence of aberrant vasculature. Prenatal sonographic detect...

Structural birth defects in the kidney and urinary tract are observed in 0.5% of live births and are a major cause of end-stage renal disease, but their genetic aetiology is not well understood. Here we analyse 135 lines of mice identified in large-scale mouse mutagenesis screen and show that 29% of mutations causing congenital heart disease (CHD) also cause renal anomalies. The renal anomalies...

Congenital longitudinal deficiency of the fibula (CLDF) is the most common congenital defect involving the long bones. There have been many different classifications developed for fibula deficiency. Achterman and Kalamchi's classification is most commonly used and will be described. Our case was complied with type II. Other anomalies includes cardiac anomalies, thrombocytopenia absent-radius (T...

Hepatoblastoma (HB) is a rare tumor of infancy and childhood manifesting with hepatomegaly and abdominal distention. It is seen with increased frequency in association with congenital hemihypertrophy and renal anomalies. Metastases to other organs, including the lungs, lymph nodes and even ovaries is well known. But cerebral metastasis of this tumor, especially in the absence of metastasis ...

in this descriptive study, researchers determined rate and type of newborn infants’ anomalies in rafsanjen niknafas hospital in 1991-1995.  this study is resulted from medical records of mothers referring to above mentioned center during five years. total number of child birth was 21187. 17321 was normal vaginal delivery and 3866 was cesarean section. because of unknown reasons, 57 infants were...

Congenital anomalies of the spine may occur with malformations of the central nervous, cardiovascular, gastrointestinal, respiratory, and genitourinary systems. This is a case of myelomeningocele with unilateral right renal agenesis in a newborn. The patient suffered complications of cerebrospinal fluid leak and meningitis, but was successfully treated and discharged on day 86. In this case, un...

hepatoblastoma (hb) is a rare tumor of infancy and childhood manifesting with hepatomegaly and abdominal distention. it is seen with increased frequency in association with congenital hemihypertrophy and renal anomalies. metastases to other organs, including the lungs, lymph nodes and even ovaries is well known. but cerebral metastasis of this tumor, especially in the absence of metastasis to o...

Introduction and Aims. Congenital absence of the vas deferens is an uncommon anomaly and this clinical condition is responsible for up to 1-2% of male infertility. It can be either unilateral or bilateral and the associated anomalies include cryptorchidism, seminal vesicles and ejaculatory ducts anomalies, and renal anomalies such as renal agenesis. We hereby present a case of congenital unilat...