The effect of cyclopropane on contractile performance of papillary muscles obtained from cats with congestive heart failure induced by pulmonary artery constriction was studied and compared with non-operated normal animals. A significant depression of contractile performance in the papillary muscles of cats with congestive heart failure was observed along with elevated right ventricular pressur...

BACKGROUND In animal studies and a pilot trial in patients with congestive heart failure, the thyroid hormone analog 3,5 diiodothyropropionic acid (DITPA) had beneficial hemodynamic effects. METHODS AND RESULTS This was a phase II multicenter, randomized, placebo-controlled, double-blind trial of New York Heart Association class II to IV congestive heart failure patients randomized (2:1) to D...

Five patients with only mildly dilated ventricles but other features typical of congestive cardiomyopathy underwent cardiac transplantation for class IV NYHA heart failure. The findings of clinical studies, cardiac catheterization, endomyocardial biopsy, and pathologic examination of the removed hearts in this group with mildly dilated congestive cardiomyopathy (MDCM) were compared with similar...

Dulaglutide is being extensively used for non-insulin-dependent diabetes mellitus and congestive heart failure also as an off-label weight loss aid. Due to its wide use, we had shed some light on this rare finding of normal lipase level in a patient with signs symptoms suggestive acute pancreatitis. A high index clinical suspicion pancreatitis despite should warrant low threshold radiological i...

Nifedipine, a calcium antagonist with strong vasodilatating effects, has been successfully used in the treatment of angina pectoris. To investigate if it can be used as a vasodilator in patients with congestive heart failure, nifedipine 20 mg was administered sublingually to 11 patients with chronic heart failure. The clinical diagnosis was congestive cardiomyopathy in 10 and severe mitral regu...

To assess the hemodynamic effects of digoxin (0.01 mg/kg) on congestive heart failure, we evaluated 19 patients with decreased contraction force of left ventricle (old myocardial infarction n = 9, and dilated cardiomyopathy n = 10, group 1) and 8 patients with mechanical impaired left ventricular filing (mitral stenosis n = 8, group 2). In groups 1 and 2, heart rate and pulmonary capillary pres...

objective: congestive heart failure (chf) has become one of the most important health care problems in western countries. this article focuses on the outpatient diagnosis and management of heart failure. we want to compare the outcome of patients who were treated with high dose diuretics in the emergency department (ed) without admission with patients who were admitted to hospital for standard ...