نتایج جستجو برای: conjugated estrogen

تعداد نتایج: 69623  

Journal: :Circulation 1998
S E Reis V Bhoopalam K A Zell P J Counihan A J Smith S Pham S Murali

BACKGROUND Transplant-associated coronary arteriopathy is manifested in its early stages by paradoxical coronary artery constriction in response to endothelium-dependent vasodilator stimuli such as the cold pressor test (CPT) and is a major cause of death or retransplantation. Estrogen has vasoactive properties that abolish coronary artery endothelial dysfunction in native hearts. We hypothesiz...

Abbas Bahreini Behrooz Barati, Hosein Mohammadi, Masumeh Saeidi, Mohammad Ali Kiani, Seyed Amirhosein Ghazizadeh Hashemi

Introduction: Acute skin wound healing is a complicated process comprising various phases. Recent animal studies have shown that steroid sex hormones such as estrogen maybe helpful in the regulation of several pathophysiologic stages that are involved in wound healing. In this study we examined the effects of topical estrogen in the treatment of traumatic facial wounds.   Materials and Methods:...

Journal: :Circulation 2001
A Wakatsuki Y Okatani N Ikenoue T Fukaya

BACKGROUND Estrogen increases endothelium-dependent vasodilation in postmenopausal women. However, use of progestins in combination with estrogen may counter beneficial effects of estrogen on endothelium. We investigated the effect of medroxyprogesterone acetate (MPA) on estrogen-induced increase in endothelium-dependent vasodilation in postmenopausal women. METHODS AND RESULTS Postmenopausal...

Journal: :Pharmacological reports : PR 2006
Bogusław Czerny Maria Teister Zygmunt Juzyszyn Adam Kamiński Andrzej Pawlik

The selective estrogen receptor modulators tamoxifen and raloxifene represent a major therapeutic advance for clinical practice. Unlike estrogens, which are uniformly agonists, tamoxifen and raloxifene exert selective agonistic or antagonistic effects on various estrogen target tissues. The aim of the study was to evaluate the influence of tamoxifen and raloxifene on the conversion of cholester...

Journal: :Archives of internal medicine 2009
Carolyn J Crandall Aaron K Aragaki Rowan T Chlebowski Anne McTiernan Garnet Anderson Susan L Hendrix Barbara B Cochrane Lewis H Kuller Jane A Cauley

BACKGROUND Estrogen plus progestin therapy increases breast cancer incidence and breast tenderness. Whether breast tenderness during estrogen plus progestin therapy is associated with breast cancer risk is uncertain. METHODS We analyzed data from the Women's Health Initiative Estrogen + Progestin Trial, which randomized postmenopausal women with an intact uterus to receive daily conjugated eq...

2017
Seyed Asadollah Mousavi Vahid Moazed Niayesh Mohebbi Molouk Hadjibabaie Kamran Alimoghaddam Babak Bahar Mohammad Jahani Ardeshir Ghavamzadeh

Background: Hemorrhagic cystitis (HC) is one of the most challenging complications in hematopoietic stem cell transplantation (HSCT). Estrogen is one of the suggested treatments for controlling this problem. Subjects and Methods: We performed a randomized case-control study to evaluate the efficacy of oral conjugated estrogen on HC management in 56 HSCT patients. Patients were randomly assigned...

Journal: :Hypertension 2010
Laura Novensa Jana Selent Manuel Pastor Kathryn Sandberg Magda Heras Ana Paula Dantas

Conjugated equine estrogen therapy is the most common hormone replacement strategy used to treat postmenopausal women. However, the ability of an individual conjugated equine estrogen to modulate NO production and, therefore, to induce cardiovascular protection is largely unknown. The effects of equine and naturally occurring estrogens on NO generation were evaluated in human aortic endothelial...

Journal: :Circulation 2003
Akihiko Wakatsuki Yuji Okatani Nobuo Ikenoue Koichi Shinohara Kazushi Watanabe Takao Fukaya

BACKGROUND Estrogen replacement therapy (ERT) has an antioxidant effect that opposes the oxidation of LDL. Oral ERT-induced increases in plasma triglyceride, however, are associated with decreased LDL size, which may counteract this antioxidant effect. Because lower doses of oral estrogen do not affect plasma triglyceride concentrations, LDL size might not change, and the antioxidant effect of ...

Journal: :Synapse 1998
L Xiao J B Becker

Based upon the observation that estrogen acts in the striatum to rapidly modulate dopamine (DA) neural transmission and DA-mediated behaviors, it has been postulated that these effects of estrogen are mediated by a specific, membrane-bound receptor mechanism. To further characterize the pharmacological specificity of the estrogen binding site, the present experiments examine effects of various ...

Journal: :Arteriosclerosis 1990
E Barrett-Connor M Laakso

We report the fasting and post-challenge plasma insulin and glucose levels in 469 nondiabetic postmenopausal women from the Rancho Bernardo cohort according to the current use of estrogen replacement therapy. In these older women, the use of noncontraceptive estrogen was not associated with impaired glucose tolerance. Estrogen-treated women had lower levels of insulin than women who were not ta...

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