Ebola virus is one of only two known members of a family of RNA viruses, the Filoviridae. (The other member is the Marburg virus.) The Filoviridae consists of enveloped viruses containing a non-segmented negative-stranded RNA genome. The Ebola genome shows a linear gene arrangement in the order 3' untranslated region -nucleoprotein (NP) -viral structural protein -(VP) 35 -VP40 -glycoprotein (GP...

infectious bronchitis virus (ibv) is a contagious pathogen in fowl that results in economic loss in the poultry industry. in this study, the amino acids sequences of three structural proteins m, n, and s1 for five iranian ibv isolated during 1998-2011 have been analyzed. conserved and variable regions, hydrophobic characteristics and identity matrix were determined after alignment by bioedit ve...

The complete nucleotide sequence of two Xenopus actin genes encoding cytoskeletal protein isoforms has been determined. Transcripts from these genes are remarkably similar in nucleotide sequence throughout their length and code for type-5 and type-8 cytoskeletal actins. Both share some sequence homology with human gamma-actin mRNA within the 3' untranslated region but none with the equivalent r...

Nonsense-mediated decay (NMD) pathways for detection and degradation of transcripts containing premature termination (stop) codons (PTCs) are ubiquitous among the eukaryotes. NMD uses the presence of a second signal downstream of a termination codon to distinguish a PTC from a true stop codon. In mammals and perhaps other eukaryotes, the second signal is a protein complex closely associated wit...