isolated five known iridoids glycosides (scrophuloside a, harpagoside b, 5-hydroxyloganin, 8-o-acetylharpagide and 6-o-methyl,1-glucopyranosyl catalpol ),one phenyl ethanoid glycoside (verbascoside) and a phenyl ethanol amine (2-(4-chlorobenzyl amino) ethanol ) compound from the methanolic extract of aerial parts of scrophularia oxysepala using by high performance liquid chromatography based on...

PURPOSE To determine whether daily irrigation with sterile saline solution during silicone hydrogel (SiH) contact lens continuous wear (CW) can mitigate increases in corneal epithelial permeability (Pdc) and reduce the risk of adverse events. METHODS In this study, 161 non-contact lens wearers were fit with SiH contact lenses and randomized to either a treatment (n = 81) or control (n = 80) g...

QSAR for honey bee acute contact toxicity (ester derivatives) 1.2.Other related models: QSAR for honey bee acute contact toxicity (amine derivatives) QSAR for honey bee acute contact toxicity (amide derivatives) QSAR for honey bee acute contact toxicity (ether derivatives not containing amide groups) 1.3.Software coding the model: QSARModel 3.5.0 Molcode Ltd., Turu 2, Tartu, 51014, Estonia http...

Purpose: Studying the assortment of herbal medicines (HMs) available in Russian Federation, and generalizing use experience them gastroenterological practice. Methods: Information analytical. Results: The analysis State Register Medicines Permitted for Use Medical Practice, as well foreign domestic publications from authoritative international databases, has been carried out. limited range drug...

Cases of rodenticide poisoning (second-generation long-acting dicoumarin rodenticide, superwarfarin) have occasionally been reported. The main symptoms of bromadiolone poisoning are skin mucosa hemorrhage, digestive tract hemorrhage, and hematuresis. However, the symptoms of central nervous system toxicity have rarely been reported. Our case reports on a 41-year-old male who had no contact with...

Results Between October 2009 January 2010, we identified 1 imported case of KPC (origin, Southern Italy) and 3 cases of NDM-1 producing Enterobacteriaceae, transferred from hospitals in India (1), Pakistan (2) and Serbia/ France(3). Patient 1on admission digestive carrier of E. coli blaNDM-1. Patient 2digestive carrier of P. mirabilis blaNDM-1 detected after extended hospitalization and antibio...

PURPOSE Delayed diarrhea is the most important side effect of irinotecan. The aim of this study was to investigate the role of intestinal microflora on the induction of systemic and intestinal toxicity and diarrhea, studying germ-free and holoxenic mice i.p. injected with irinotecan. EXPERIMENTAL DESIGN To evaluate the lethal dose, starting with 100 mg/kg/4 d, we treated the holoxenic mice wi...

conclusions tg showed protective effect against ethanol induced gastric ulcer. this study confirmed traditional medicine claims of tg. objectives the aim of the present study was to determine the acute toxicity and protective effect of hydroalcoholic extract of tg (hetg) against ethanol induced gastric ulcer. materials and methods male wistar rats were divided into five groups (n = 7). hetg at ...

new sources of botanical pesticides in the management of sitotroga cerealella (olivier) infesting rice grains are indispensable in farmers’ quest towards achieving maximum protection of their rice produce. in this study, the efficacy of root and stem bark of cleistopholis patens as an insecticidal agent against s. cerealella was investigated at 28 ± 2 ºc and 75 ± 6% relative humidity. moths wer...