background: degenerative joint disease (djd) is the most common joint disease in human beings. previous studies have explained that glucosamine is preferred as placebo and in efficacy compared with nsaid’s in treatment of patients’ knee osteoarthritis. alendronate was used to treat osteoporotic patients and its efficacy was established. objectives: the aim of this study was to compare the effic...

attention-deficit/hyperactivity disorder is one of the most common mental disorders in childhood, and it continues to adulthood without proper treatment. stimulants have been used in the treatment of attention-deficit/hyperactivity disorder (adhd) for many years, and the efficacy of methylphenidate in the treatment of adults with adhd has been proven to be acceptable according to meta-analysis ...

clinical trial committee (ctc) has been established in food and drug organization (fdo), in 2003 to assure efficacy and safety of all types of medicinal products which are meant to be registered in iran drug list and/or obtain market authorization.all clinical trial files, meeting minutes and databases in ctc secretariat in fdo were reviewed. relevant information and data extracted, analyzed an...

conclusions project management may benefit both the managerial and scientific aspects of medical projects and reduce fund waste. however, little has been written to date on project management in the context of clinical research. the suggestions represent the views of the individual authors. to provide a high level of evidence in this regard, we recommend that a randomized controlled trial be pe...

conclusions the evidence that btx-a decreases ntg-induced cgrp-li and sp-li levels in trigeminovascular system suggests that btx-a attenuates migraine by suppression of neuropeptide release. btx-a injections for migraine at acupoint-sites and fixed-sites are effective. acupoint-sites btx-a administration shows more efficacy for migraine than fixed-sites application. results local btx-a injectio...

background: intrauterine insemination (iui) is one of the most appropriate and cost-effective methods in infertility treatment. objective: we aimed to investigate effect of vaginal misoprostol on pregnancy rate after iui. materials and methods: two hundred and ten infertile women who were referred to infertility clinic of alzahra hospital by an indication of iui during 2012-2013 were randomly a...

background: hepatorenal syndrome (hrs) is known as development of acute renal failure in a patient who usually has advanced liver disease. the aim of the present study was to determine the safety and the efficacy of noradrenalin in comparison with midodrine‑octreotide in patients with hrs. methods: this study was registered to the iranian registry of clinical trials (irct). this study was a sin...

background: poor sleep quality (sq) is common among patients after coronary artery bypass graft surgery (cabg). this study attempted to determine the status of sq following an intervention based on the precede-proceed model in patients with poor sq after cabg. methods: this study was a randomized clinical trial. the study sample, including 100 patients referred to the cardiac rehabilitation cli...