background: onchocerciasis is endemic in the imo river basin, nigeria. this study was aimed at assess­ing the prevalence and intensity of microfilaria of onchocerca volvulus in the area. methods: a cross-sectional study was carried out in the okigwe local government area, imo state, nige­ria. two skin snips (one from the waist and another from the shoulder) were taken from 1024 individu­als exa...

Chromosomal translocations between antigen receptor loci and oncogenes are a hallmark of lymphoid cancers. Several new studies now reveal that programmed DNA breaks created during assembly of antigen receptor genes can be channeled into an alternative DNA end-joining pathway that is implicated in the chromosomal translocations of lymphoid cancers (Corneo et al., 2007; Soulas-Sprauel et al., 200...

Purpose Therapies for limbal stem cell deficiency (LSCD) include stem cell (SC) grafts that regenerate the damaged ocular surface. However, the fate of transplanted cells is ill-defined. We addressed this limitation using primary corneal epithelial cells from K14-Confetti mice. Methods Cultures of primary corneo-limbal epithelia were generated from K14-Confetti (n = 6) and wild-type (WT) (n =...

The lens was removed using the ab externo approach with a limbal-based flap and corneo-scleral section, followed by a round pupil cryoextraction with or without zonulysin. The zonulysin used was o05 to i ml. Chymozym (Ikapharm) containing I63 to 332 Anson proteolytic units. Postoperatively the patients received atropine and antibiotic drops. Steroid drops were started on the third postoperative...

PURPOSE To report a case of beta-hemolytic streptococcal endophthalmitis following crane-pecking injury. CASE REPORT A twelve-year-old boy was brought to us by his father with history of crane beak injury in his right eye. On examination, his vision was 6/24 Snellen's acuity. Anterior segment examination showed a full thickness two mm corneo-limbal tear at 1 o'clock with iris prolapse. Pupil ...