INTRODUCTION The accumulation of visceral fat affects the metabolism of hormones and some nutrients, but these mechanisms remain unclear. OBJECTIVE To assess the influence of cortisol on the metabolism of zinc in morbidly obese women. METHOD Cross-sectional, case-control study involving 80 women aged between 20 and 59 years. The participants were divided into two groups: experimental (morbi...

James I. %Vessel, B.S.; and Brandon Taylor, B.S. G lucocorticoids have been recognized to play an important role in lung development in utero.’ The identification of specific receptors for cortisol in both the cytosol and nuclear fraction of fetal lung homogenates supports the concept that the lung is an important target tissue for this steroid.2.3 Administration of cortisol to rabbit fetuses a...

Purpose: Comprehensive monitoring of bull-and-pystroy bull-producers the Yenisei type with different blood and hormonal indicators serum on day seed. Materials methods. The work was carried out manufacturers Red-Pesostroy in amount 12 heads, at age 19-31 months. We studied a protein-lipid, mineral metabolism, vitamin-farmenting state level endogenous hormones: testosterone, estradiol, cortisol,...

Hydrocortisone replacement therapy is a cornerstone in the treatment of adrenal insufficiency (AI). While urinary cortisol has been used as a diagnostic tool for AI, it remains unclear whether it is a useful parameter to monitor hydrocortisone replacement therapy. Aim of this study was to evaluate possible differences in cortisol metabolism between adrenal insufficient patients and healthy subj...

Previous studies in our laboratory have shown that a modest chronic increase in maternal cortisol concentrations impairs maternal glucose metabolism and increases the incidence of perinatal stillbirth. The dramatic outcomes prevented our ability to study the effects of maternal hypercortisolemia on neonatal growth, glucose metabolism, and hypothalamo-pituitary-adrenal axis response. Therefore, ...

CONTEXT The metabolic syndrome (MetS) is a cluster of metabolic abnormalities that increase the risk for type 2 diabetes mellitus and vascular disease. The common characteristics of MetS and hypercortisolemic conditions such as Cushing's syndrome (CS) suggest that the pathogenesis of MetS and central obesity might involve prolonged and excessive exposure to glucocorticoids. The present review s...

Stress is a non specific response of the body ,when exposed to any demanding situation. A slight increase in cortisol levels,cortisol being the major stress hormone implicated in stress, has positive effects like increased energy, increased memory and decreased pain sensitivity.However, prolonged increase in cortisol levels can disrupt blood sugar metabolism, trigger emotional problems and elic...

In rat thymus cells incubated with carbohydrate substrate the steady state rate of incorporation of uridine into RNA generally parallels the rate of incorporation of amino acids into protein. In both instances glucose is required for continued maximal incorporation rates, a requirement that is only partially satisfied by other readily metabolized substrates such as pyruvate, lactate, or /3-hydr...

In previous studies (l-3) cortisol (hydrocortisone) was isolated and identified from the urine of the normal and the scorbutic guinea pig. However, paper partition chromatography of extracts of guinea pig urine (2) revealed that in addition to cortisol several other blue tetrazolium-reducing steroids were present. The possibility existed that some of these steroids were metabolites of endogenou...