INTRODUCTION: Secondary lymphedema is a chronic and debilitating complication of breast cancer therapy affecting more than one in five breast cancer survivors.1 In this patient population, patient-reported outcomes may be more important in predicting long-term health-related quality of life (HRQoL) than clinician measured outcomes.2 Cost-effectiveness analysis can be used to compare different t...

INTRODUCTION: Secondary lymphedema is a chronic and debilitating complication of breast cancer therapy affecting more than one in five breast cancer survivors.1 In this patient population, patient-reported outcomes may be more important in predicting long-term health-related quality of life (HRQoL) than clinician measured outcomes.2 Cost-effectiveness analysis can be used to compare different t...

2004;27:453e8. 9. Hillman DR, Murphy AS, Pezzullo L. The Economic Cost of Sleep Disorders. Sleep 2006;29:299e305. 10. Mar J, Rueda JR, Durán-Cantolla J, et al. The costeffectiveness of nCPAP treatment in patients with moderate-to-severe obstructive sleep apnoea. Eur Respir J 2003;21:515e22. 11. Tan MC, Ayas NT, Mulgrew A, et al. Costeffectiveness of continuous positive airway pressure therapy i...

There is a general agreement among software engineering practitioners that software inspections are an important technique to achieve high software quality at a reasonable cost. However, there are many ways to perform such inspections and many factors that affect their costeffectiveness. It is therefore important to be able to estimate this cost-effectiveness in order to monitor it, improve it,...

Depression affects one in four adults with type 2 diabetes (T2DM) and is associated with worsened diabetes complications, increased health care costs and early mortality. Rural and low-income urban areas, including the Appalachian region, represent an epicenter of the T2DM epidemic. Program ACTIVE II is a comparative effectiveness treatment trial designed to test whether a combination of cognit...

ƒ In each study, we used a simulation model to identify a subpopulation based on age and clinical risk, for whom we used genetic testing to find intensified prevention measures, which was optimally costeffective. ƒ As more genetic tests become available, this method can be used to identify screening strategies that maximize cost-effectiveness. ƒ We develop a framework for stratified costeffecti...

1. Wonderling D, Umans-Eckenhausen MA, Marks D, Defesche JC, Kastelein JJ, Thorogood M. Costeffectiveness analysis of the genetic screening program for familial hypercholesterolemia in The Netherlands. Semin Vasc Med. 2004;4(1): 97–104 2. Kavey R, Simons-Morton DG, de Jesus J. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: full re...