Excitable chemical media are amongst most promising ‘wet’ computing devices capable for solving a wide ranging of tasks from optimization, computational geometry, image processing and robot control. The excitable media can also implement functionally complete sets of logical gates thus qualifying as (logically) universal computing systems. See theoretical background and details of laboratory im...

This is the first of two papers which construct a purely algebraic counterpart to the theory of Gromov-Witten invariants (at all genera). These GromovWitten type invariants depend on a Calabi-Yau A∞ category, which plays the role of the target in ordinary Gromov-Witten theory. When the Fukaya category of a compact symplectic manifold X is used, it is shown, under certain assumptions, that the u...

Jane Costello, a mental health researcher, was at work on a long-term study of psychiatric symptoms of children in rural North Carolina, about a quarter of them from a Cherokee reservation. Midway through the study, the Cherokees opened a casino on the reservation, providing profit-sharing payments to reservation families—suddenly lifting them out of poverty. Unexpectedly, Costello and her fell...

According to Costello and Watts (2014), probability theory can account for key findings in human judgment research provided that random noise is embedded in the model. We concur with a number of Costello and Watts's remarks, but challenge the empirical adequacy of their model in one of their key illustrations (the conjunction fallacy) on the basis of recent experimental findings. We also discus...

Abstract We relate two formalisms recently proposed for describing classical integrable field theories. The first (Costello and Yamazaki in Gauge Theory Integrability, III, 2019) is based on the action of four-dimensional Chern–Simons theory introduced studied by Costello, Witten Yamazaki. second Yamazaki, 2017) makes use generalised Gaudin models associated with untwisted affine Kac–Moody alge...

We report the case of 17-year-old female diagnosed with Costello syndrome. Genetic testing provided a proof with G12S mutation in the HRAS gene since 3 years of age with a presentation of severe nodulocystic acne on her face. After 2 months of oral isotretinoin treatment, improvement in her acne was observed. Interestingly, an unexpected significant improvement of acanthosis nigricans on her ne...

I always knew Daisy would die before reaching adulthood. She was my fourth child, born prematurely in December 2004 with a severe form of rare genetic condition called Costello syndrome. Daisy required complex care, but every decision about her care was made on the basis of improving the quality of her life, which meant helping her do the things she loved, such as being at home with her family,...