We compared the efficacy and tolerability of controlled-release carbamazepine (CBZ-CR) with conventional carbamazepine (CBZ) in 131 epileptic patients (both men and women, ages 6-65 years) in an open, multicentre, cross-over trial. Patients entered into the trial were previously on CBZ monotherapy or polytherapy. During the first 4 weeks, patients were treated with equivalent daily doses of CBZ...

The previously developed enantioselective iodocyclization of gamma-hydroxy-cis-alkenes required 30 mol% of (R,R)-salen-Co(II) complex as chiral catalyst and 0.75 equivalent of N-chlorosuccinimide (NCS) as activator to produce 2-substituted tetrahydrofurans with 61 to 90% ee. Due to the considerable loading amount of the Co(II) complex, another more effective catalyst was pursued by screening (R...

High concentrations of hexavalent chromium [Cr(VI)] in drinking water induce villous cytotoxicity and compensatory crypt hyperplasia in the small intestines of mice (but not rats). Lifetime exposure to such cytotoxic concentrations increases intestinal neoplasms in mice, suggesting that the mode of action for Cr(VI)-induced intestinal tumors involves chronic wounding and compensatory cell proli...

We study real-analytic Levi degenerate hypersurfaces M in complex manifolds of dimension 3, for which the CR-automorphism group Aut(M) is a real Lie group acting transitively on M . We provide large classes of examples for such M , compute the corresponding groups Aut(M) and determine the maximal subsets of M that cannot be separated by global continuous CR-functions. It turns out that all our ...

Five non-precious Ni-Co based alloys were analyzed with respect to their corrosion behaviour. The correlation between the amount of the elements Cr, Mo, V and the corrosion behaviour, expressed by the PREN (pitting resistance equivalent number) index in the case of the allied steels, was extended for Ni-Cr and Co-Cr dental alloys characterization. Open circuit potential, corrosion current densi...

Given N a non generic smooth CR submanifold of C, N = {(N, h(N))} where N is generic in C and h is a CR map from N into C. We prove, using only elementary tools, that if h is decomposable at p′ ∈ N then any decomposable CR distribution on N at p = (p′, h(p′)) extends holomorphically to a complex transversal wedge. This gives an elementary proof of the well known equivalent for totally real non ...

We discuss a sharp lower bound for the first positive eigenvalue of the sublaplacian on a closed, strictly pseudoconvex pseudohermitian manifold of dimension 2m + 1 ≥ 5. We prove that the equality holds iff the manifold is equivalent to the CR sphere up to a scaling. For this purpose, we establish an Obata-type theorem in CR geometry which characterizes the CR sphere in terms of a nonzero funct...

PURPOSE To analyze the causes of anisometropia. METHODS Between June 2011 and November 2012 101 participants were divided into three groups. The refraction comprising the degree of refractive errors in the presence of astigmatism which was converted into the degree of spherical equivalent as well as ocular axial length (AL), corneal curvature (CR), average corneal power (ave K) and diopters w...

CR singularities of real threefolds in C4 are classified by using holomorphic coordinate changes to transform the quadratic part of the real defining equations into one of a list of normal forms. In the non-degenerate case, it is shown that a real analytic manifold near a CR singular point is formally equivalent to a real algebraic model. Some degenerate cases also have this property.