long-chain diacrylate crosslinkers based on linear α,ω-diols were synthesized and characterized using ftir and 1h nmr spectroscopy. the highest reaction yield (99.5%) was due to polyethylene glycol diacrylate 1000 (pegda-1000). then, kaolin-containing poly(potassium acrylate-acrylic acid) superabsorbent composites and kaolin-free counterparts were synthesized using pegda-1000.the effect of the ...

The nanoparticles of templated crosslinked chitosan, was prepared through using ECH as a crosslinker. The nanoparticles exhibited significantly higher adsorption capacities from the congo red dye than other adsorbent formed without a crosslinker. The adsorption of the dyes on the nanoparticles was affected by the initial pH, dye concentration, and temperature. The results were in accordance wit...

A class of new biodegradable hydrogels based on poly(ethylene glycol) methacrylate-graft-poly(glutamic acid) and poly(ethylene glycol) dimethacrylate was synthesized by photoinduced polymerization. Because all the polymeric constituents were highly hydrophilic, crosslinking could be performed in aqueous solutions. This type of crosslinked hydrogel was prepared by modifying a select number of ac...

Classical Molecular Dynamics (MD) simulations provide insight into the properties of many soft-matter systems. In some situations, it is interesting to model the creation of chemical bonds, a process that is not part of the MD framework. In this context, we propose a parallel algorithm for step- and chain-growth polymerization that is based on a generic reaction scheme, works at a given intrins...

Using the inclusion complex of trans azobenzene and cyclodextrin as a photo-switchable crosslinker, a dextran based photo-responsive hydrogel system has been constructed and employed for a light controlled protein release system.

Recent development of high-resolution mass spectrometry (MS) instruments enables chemical crosslinking (XL) to become a high-throughput method for obtaining structural information about proteins. Restraints derived from XL-MS experiments have been used successfully for structure refinement and protein–protein docking. However, one formidable question is under which circumstances XL-MS data migh...

Here we describe a novel crosslinker and its application as a biotin-transfer reagent to identify cell surface receptors of soluble protein ligands on live cells. This crosslinker contains three functional groups: an aldehyde-reactive aminooxy group, a sulfhydryl, and a biotin (ASB). It is readily synthesized via a 3-step addition reaction using standard solid-phase peptide synthesis methods an...