The Masson-Fontana silver stain for melanin was employed for the differentiation of pathogenic fungal species in human or mouse tissues. The fungi studied were Candida albicans, Candida tropicalis, Candida glabrata (Torulopsis glabrata), Cryptococcus neoformans, Cryptococcus bacillisporus, Coccidioides immitis, Blastomyces dermatitidis, Histoplasma capsulatum, Paracoccidioides brasiliensis, Spo...

Cryptococcus neoformans is an environmental fungus that causes pulmonary and central nervous system infections. It also responsible for 15% of AIDS-related deaths.

There are over one million fungal species in nature, but only a handful of them cause human diseases. A variety of distinct factors aid the virulence of fungi in their transition from environmental reservoirs to mammals. One important factor is their ability to acquire nutrients efficiently so that they can survive and thrive in a nutrient-limiting host environment. The human fungal pathogen Cr...

Infections due to Cryptococcus are a leading cause of fungal infections worldwide and are acquired as a result of environmental exposure to desiccated yeast or spores. The ability of Cryptococcus to grow, mate, and produce infectious propagules in association with plants is important for the maintenance of the genetic diversity and virulence factors important for infection of animals and humans...

The presence of Cryptococcus gattii was investigated in different regions of the State of Espírito Santo. The largest number (73) of samples was collected from trees located in public places in Vitória; 47 came from preserved areas or areas with only minor human impact, surrounding this city, at altitudes from 0 to 900m above sea level; 48 came from trees native of the northern and southern reg...

Cryptococcus neoformans is the most common cause of fungal meningitis, with high mortality and morbidity. The reason for the frequent occurrence of Cryptococcus infection in the central nervous system (CNS) is poorly understood. The facts that human and animal brains contain abundant inositol and that Cryptococcus has a sophisticated system for the acquisition of inositol from the environment s...

EN: erythema nodosum PCC: primary cutaneous cryptococcal INTRODUCTION Members of the Cryptococcus genus are opportunistic encapsulated yeasts that cause significant morbidity and mortality most often in immunocompromised hosts. Clinically, cryptococcal infections manifestmost commonlyasmeningitis or a respiratory infection. The cryptococcal species are Cryptococcus neoformans, Cryptococcus gatt...

The fungal pathogens Cryptococcus neoformans and Cryptococcus gattii can cause life-threatening infections in immune compromised and immune competent hosts. These pathogens enter the host via inhalation, and respiratory tract innate immune cells such as dendritic cells (DCs) are one of the first host cells they encounter. The interactions between Cryptococcus and innate immune cells play a crit...

Background and Purpose Cryptococcus species are pathogenic and non-pathogenic basidiomycete yeasts that are found widely in the environment. Based on phenotypic methods, this genus has many species; however, its taxonomy is presently being re-evaluated by modern techniques. The Cryptococcus species complex includes two sibling taxa of Cryptococcus neoformans and Cryptococcus gattii. We aimed to...