cluding Curcuma longa, C. zedoaria, etc. have attracted attention because of their antiinflammatory, antihepatotoxic, and neuroprotective activity. These drugs were originally used in traditional Asian medicines, and in Chinese medicine they are mainly used for treating various syndromes due to obstruction of blood circulation and retention of blood stasis such as arthralgia, psychataxia, and d...

Ethanolic extract of Curcuma xanthorrhiza was used to evaluate the analgesic and toxicity effects in vivo. The extract was standardized using GC-MS, which showed that 1 mg of Curcuma xanthorrhiza ethanolic extract contains 0.1238 mg of xanthorrhizol. The analgesic activity was studied in rats using three different models, namely the hot plate test, tail flick test and formalin-induced pain test...

The study aimed to compare the anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. Chen et C. Ling (Curcuma wenyujin) and Scutellaria baicalensis Georgi (Scutellaria baicalensis). This study used three parts to compare the two herbs. Firstly, animals were randomly divided into a Scutellaria baicalensis group, a Curcuma wenyujin group, an indomethacin group, and a model-co...

Curcumin, an aromatic phytoextract from the turmeric (Curcuma longa) rhizome, has been used for centuries for a variety of purposes, not the least of which is medicinal. A growing body of evidence suggests that curcumin has a broad range of potentially therapeutic pharmacological properties, including anti-inflammatory, anti-fibrotic, and anti-neoplastic effects, among others. Clinical applicat...

Objective. To evaluate the effect of petroleum ether extracts of Curcuma zedoaria on the proliferation of human triple negative breast cancer cell line MDA-MB-231. Methods. The reagents were isolated from Curcuma zedoaria by petroleum ether fraction. It was assayed by CCK8 for MDA-MB-231 cellular viability with various concentrations and days, cell cycle analyses, Western Blot analysis, and Rea...

Introduction: Curcuma amada Roxb. usually referred as ambahaldi is an exceptionally aromatic rhizomatic herb which contains number of phyto constituents responsible for several pharmacological activities. Present study attempt to explore antioxidant and analgesic activity ethanolic extract C. amada. Objectives: The goal this work was assess the Methods: For in-vitro study, DPPH (2, 2-Diphenyl-1...

BACKGROUND Supra-nutritional doses of curcumin, derived from the spice Curcuma longa, have been proposed as a potential treatment of inflammation and metabolic disorders related to obesity. The aim of the present study was to test whether Curcuma longa extract rich in curcumin and associated with white pepper (Curcuma-P®), at doses compatible with human use, could modulate systemic inflammation...

From the methanolic extract of the rhizomes of Curcuma comosa cultivated in Thailand, six new sesquiterpenes, (+)- and (-)-comosols (1, 2), comosones I (3), II (4), and III (5), and dimethoxycurcumenone (6), were isolated. Their structures were elucidated on the basis of chemical and physicochemical evidence.

Curcuma spp. extracts, particularly the dietary polyphenol curcumin, prevent colon cancer in rodents. In view of the sparse information on the pharmacodynamics and pharmacokinetics of curcumin in humans, a dose-escalation pilot study of a novel standardized Curcuma extract in proprietary capsule form was performed at doses between 440 and 2200 mg/day, containing 36-180 mg of curcumin. Fifteen p...

Shamima Akhtar SHARMIN, Mohammad Jahangir ALAM, Md. Mominul Islam SHEIKH, Rashed ZAMAN, Muhammad KHALEKUZZAMAN, Sanjoy Chandra MONDAL, Mohammad Anwarul HAQUE, Mohammad Firoz ALAM, Iftekhar ALAM* Division of Applied Life Sciences (BK21 Program), College of Agriculture and Life Science, Gyeongsang National University, Jinju, Republic of Korea Department of Bioscience (Integrated Bioscience Sectio...