Pseudolymphomatous folliculitis (PLF), which sometimes mimicks cutaneous lymphoma, is a rare manifestation of cutaneous pseudolymphoma and cutaneous lymphoid hyperplasia. We describe a 57-year-old Japanese woman with PLF on the nose that resembled cutaneous lymphoma clinically. The biopsy specimen revealed dense lymphocytes, especially CD1a+ cells, infiltrated around the hair follicles. Without...

We describe a patient with primary cutaneous small-tomedium--sized CD4+ T-cell lymphoma, according to the most recent World Health Organization (WHO) classification of cutaneous lymphomas. This lymphoma, previously known as primary cutaneous small-to-medium-sized pleomorphic CD4+ T-cell lymphoma, has a low incidence and good prognosis. The interest in the case presented in this report derives f...

CNS: central nervous system CSF: cerebrospinal fluid PCMZL: primary cutaneous marginal zone lymphoma WBC: white blood cells BACKGROUND Primary cutaneous marginal zone lymphoma (PCMZL) is an indolent B-cell lymphoma, typically characterized by frequent cutaneous recurrences and rare systemic involvement. Lymph nodes, bone, and bone marrow are commonly affected sites in rare cases of extracutaneo...

The classification of cutaneous lymphomas is multidisciplinary and requires the correlation between clinical, histopathological, immunohistochemical, and molecular diagnostic elements. In this article, we present four different cases of CD30-positive T-cell lymphoma with cutaneous manifestations. We compare cases with definitive diagnosis of papulosis lymphomatoid type C, primary cutaneous anap...

ALCL: anaplastic large cell lymphoma CL: composite lymphoma EBV: Epstein-Barr virus MF: mycosis fungoides INTRODUCTION Patients with mycosis fungoides (MF) are at increased risk of a second malignant neoplasm, especially lymphoma. We report a sexagenarian with a 14-year history of patch MF, stage IB, who had intravascular cutaneous anaplastic large cell lymphoma (ALCL) and cutaneous composite l...

Clinical features and history Cutaneous B-cell lymphomas usually present as one or more erythematous papules or nodules that may coalesce to form plaques. They are usually localized tumors effecting one cutaneous region and rarely ulcerate. There is some regional predilection for various sub-types of tumors; follicle center lymphoma more commonly arises on the scalp, marginal zone B-cell lympho...

Primary Cutaneous lymphomas of B cell origin are rare, there remains a controversy in truly classifying these lymphomas and an updated EORTC classification divides them on the basis of their distinct histopthological grounds rather than on the basis of their anatomic location as in WHO classification, while the new WHO- EORTC joint classification maintains some characteristics of both systems, ...

Extranodal natural killer/T-cell (ENK/T) lymphoma is a rare neoplasm, subcategorized into ENK/T-nasal (ENK/T-N) and ENK/T-nasal type (ENK/T-NT) lymphomas. ENK/T-NT lymphoma with initial presentation in the skin is known as primary cutaneous ENK/T-NT (PC-ENK/T-NT) lymphoma. The aim of this study was to investigate pathogenesis, genomic alterations, and prognosis of cutaneous ENK/T lymphomas to p...