Secondary transformation in Germ Cell Tumours (GCT) is an extremely rare event. We report here a case of malignant melanoma arising in primary mediastinal GCT. A young male presented with new onset dyspnoea and a mediastinal mass. As serum alpha fetoprotein was raised, a diagnosis of primary mediastinal GCT was made. He achieved remission with standard chemotherapy and resection of the mass. Af...

Sir, The development of primary choroidal and cutaneous malignant melanoma in the same patient is rare, with only 8 cases described in the literature (1 – 3). In contrast, the occurrence of primary cutaneous and choroidal melanoma in association with the atypical mole syndrome has been documented by a number of authors (2). We describe here the case of a 71-year-old man who presented initially ...

Skin cancer has become the most common neoplasm in the United States. With early diagnosis and appropriate management, most skin cancers have an overall 5-year survival rate of 95%. Cutaneous malignant melanoma (CMM), however, has a significantly higher morbidity and mortality, resulting in 65% of all skin cancer deaths. Although the long-term survival rate for patients with metastatic melanoma...

BACKGROUND ABO blood groups have been suggested to contribute to the development of certain tumors; however, the associations between ABO blood groups and the incidence and metastases of cutaneous malignant melanomas have not been fully evaluated in Chinese populations. Thus, we investigated these associations with a case-controlled study in northeast of China. METHODS A total of 482 patients...

A 73-year-old Japanese woman presented with cutaneous horn on the right cheek. The resected tumor was 9 mm in diameter, with 14 mm protrusion, and showed exophytic growth with marked papillomatosis. Histopathology showed proliferation of atypical melanocytes with melanin pigments in the epidermis and dermis under the cutaneous horn. These cells were confined to the base of the cutaneous horn, a...

Background: The incidence of cutaneous malignant melanoma (CMM) has increased continuously during recent decades among many populations the world. Cutaneous Malignant Melanoma is a malignancy with demographic and ethnic disparity located in skin mucous membranous. objective this study to determine (CM) characteristics Iran. Methods: This retrospective cross sectional study. We used data from Ra...

in order to distinguish between benign and malignant types of pigmented skin lesions, computerized procedures have been developed for images taken by different equipment that the most available one of them is conventional digital cameras. in this research, a new procedure to detect malignant melanoma from benign pigmented lesions using macroscopic images is presented. the images are taken by co...