INTRODUCTION Polyarteritis nodosa is a rare disease resulting from blood vessel inflammation (vasculitis), causing damage to organ systems and featuring an extended range of possible symptoms. The cause of polyarteritis nodosa is unknown. CASE PRESENTATION In the present report we describe the presentation and treatment of polyarteritis nodosa involving the hard palate in an 88-year-old Cauca...

A 47-year-old man was admitted to our hospital in January, 2006 because of a huge cutaneous ulcer in his lower limb. He was diagnosed with polyarteritis nodosa due to the cutaneous ulcer, mononeuritis multiplex, muscular pain, elevated serum CRP level and from histological findings of a skin biopsy. He was initially treated with 60 mg/day of prednisolone, followed by 1000 mg/day of intravenous ...

INTRODUCTION Hepatitis C virus has been under-recognized as an etiologic factor for polyarteritis nodosa and the presence of hepatitis C antigenemia in patients with polyarteritis nodosa has been reported as insignificant. In the literature hepatitis C virus-associated polyarteritis nodosa is a rare and controversial entity. CASE PRESENTATION A 34-year-old Sri Lankan Tamil man presented to ou...

POLYARTERITIS nodosa (periarteritis nodosa), first described by Kussmaul and Maier (1866), is a relatively rare disease, but considerable attention has been paid to it in recent years. Duke-Elder (1962), describing the condition, wrote: "this is a disseminated disease of obscure cause characterized by necrosing obliterative lesions of small arteries and arterioles which appear nodular owing to ...

Seckel syndrome is a rare genetic disorder with a typical "bird-headed" appearance. It could affect many organ systems but renal involvement is uncommon. Polyarteritis nodosa is systemic vasculitic disorder which also involves kidneys. We report a case of Seckel syndrome in a 9 year-old boy with renal involvement due to polyarteritis nodosa. According to the literature, this is the first report...

Abstract Cutaneous arteritis (CA) is a rare limited form of polyarteritis nodosa (PAN), which usually has benign prognosis and requires less aggressive therapy. Here, we present case CA localized to both skin muscle the same area as lesions. We propose with disorders severe subtype literature review disorders, may require treatment intravenous pulse methylprednisolone, immunosuppressive therapy...

IMPORTANCE Mutations in the CERC1 gene associated with deficiency in the ADA2 protein (DADA2) have been implicated in the pathogenesis of cutaneous polyarteritis nodosa (cPAN) and early-onset vasculopathy. DADA2 is not only limited to cPAN and vasculopathy but also includes immunodeficiency that affects several cellular compartments, including B cells; however, some patients appear to have a mo...

A 5 1/2-year-old girl presented with an acute febrile illness associated with limb and facial swelling, and a skin eruption. She was diagnosed as suffering from cutaneous polyarteritis nodosa. She was told to stay in bed and was given soluble aspirin. Now, more than 3 years later, she is well and symptom-free. The important diagnostic feature of this benign condition, which is distinct from the...