1. The physiological actions of HCN and its salts appear to be due (a) to the ease with which HCN molecules penetrate living cells and then ionizing, exert their influence by means of H ions and CN ions; (b) to the weakness of HCN as an acid, which permits at neutrality or at even slight alkalinity the presence of a considerable amount of free HCN molecules in the presence of their salts; (c) t...

A hexagonal outlined porous cladding with vacant core photonic crystal fibre (HOPC-VC-PCF) sensor using Zeonex has been presented, which can detect cyanides at the THz regime. Cyanides are incredibly lethal chemicals to humans as they rapidly cause impairment or even death; such harmful substances must be identified precisely. The proposed model analysed a broad spectrum of regimes for three di...

2,6-Dichloro-9-thiabicyclo[3.3.1]nonane, easily available by an improved condensation of sulfur dichloride, sulfuryl chloride, and 1,5-cyclooctadiene, is a well- behaved scaffold for the nucleophilic substitution of azides and cyanides via neighboring- group participation by the sulfur atom. The products are isolated in high yields with purity >95% by simple extraction and washing protocols.

A new procedure is described for the synthesis of a,/?-glycosyl cyanides by the reaction of per-O-benzylated S-a-D-glycopyranosyl phosphorothioates with trimethylsilyl cyanide in the presence of Lewis acid. Starting S-glycosyl phosphorothioates are prepared, directly, from O-benzyl protected reducing D-hexopyranoses (gluco-, galacto-, manno-) and alkylammonium salt of phosphorothioic acid under...

The use of thyroid-depressant agents in the control of hyperthyroidism has raised questions concerning their relationship to other goitrogens and their mode of action. Other problems have been encountered as well, particularly with respect to toxic reactions, the effect of preliminary iodine administraton, and the control of the hypothyroid state which may result. The information available on t...