An abnormal tendency to post-operative hmorrhage may occur in patients with severe cyanotic congenital heart disease (Blalock, 1948). In preliminary findings by Somerville and McDonald (1960) the thromboplastin generation test showed evidence of defective blood coagulation in these patients. Blood coagulation has been further investigated in patients with cyanotic and acyanotic congenital heart...

Arterial oxygen tension was measured from radial artery samples in 276 infants referred for cardiological investigation. Values obtained during air breathing in infants with congenital heart disease showed considerable overlap between 'cyanotic' and 'acyanotic' groups, and are of limited diagnostic use. By contrast, values obtained while breathing oxygen in concentrations of over 80%, measured ...

We report the case of a 39-year-old male with complex cyanotic congenital heart disease undergoing emergency craniotomy for a cerebral abscess. Maintenance of intraoperative hemodynamic stability and adequate tissue oxygenation during anesthesia may be challenging in patients with cyanotic congenital heart disease. In this case, we decided to perform the surgery as an awake craniotomy after int...

Angiogenesis is largely an adaptive response to tissue hypoxia, which occurs in a wide variety of situations. Interestingly, the extent of hypoxia-induces angiogenesis in the cardiac muscle of children diagnosed with congenital cyanotic heart defects is not well established. Thus, the aim of this study was to 1) estimate the cardiac muscle microvessel density (MVD) in children diagnosed with cy...

The surgical treatment of cyanotic heart disease in the adult poses some technical difficulties in correcting severe anatomical deformities and compromised physiological states over a wide range of conditions. Various abnormalities and their surgical management have been reviewed. Forty-six patients over the age of 18 years have been operated with 10 operative deaths. Of the survivors, 63% have...

BACKGROUND/AIM Ghrelin has effects on nutrient intake and growth. The cause of growth retardation in congenital heart disease is multifactorial. The aim of the present study is to investigate the ghrelin in congenital heart disease and the association of ghrelin with TNF-alpha and IL-6. Materials and methods. We measured serum ghrelin, TNF-alpha, and IL-6 levels using specific immunoassay in 68...

Univentricular dextrocardia is a rare complex congenital cyanotic heart disease. With the improvement of medical and surgical care, greater number women with diseases have survived up to childbearing age. Pregnancy univentricular Fontan circulation increases maternal fetal mortality morbidity. We report case successful management two pregnancies in woman repaired dextrocardiac heart.