results abnormal liver function test was detected in cf patients. as well, liver sonogram was abnormal in approximately one-third of the patients. this study showed a higher prevalence of biochemical abnormality in patients with abnormal livers ultrasonography. conclusions noninvasive paraclinical evaluation methods could be recommended in the patients with cf for early detection of silent live...

Cystic fibrosis is an autosomal recessive disease caused by a wide spectrum of mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator protein. These mutations that correlate with different phenotypes, vary in their frequency and distribution in different populations. In this study missense mutation R117H that associated with the different clinical symptoms wa...

conclusions the incidence of mbls producing p. aeruginosa in patients with cf was not low. the findings indicate that the identification of drug-resistance patterns in p. aeruginosa and the detection of mbl-producing isolates are important in the prevention and control of infections. background respiratory infections caused by pseudomonas aeruginosa play an important role in the pathogenesis of...

A method that maximises the yield of viable enterocytes has been developed for the isolation of enterocytes from human jejunal biopsy specimens. These enterocytes have been used to study the values of intracellular free calcium and the rises in adenosine 3'5'-cyclic monophosphate (cAMP) induced by secretagogues in normal and cystic fibrosis cells. Basal intracellular free calcium of cystic fibr...

Cystic fibrosis is the most common autosomal recessive hereditary disease in white populations. It characterized by formation of abnormal secretions exocrine glands located sweat and salivary glands, tracheobronchial tree, large intestine, pancreas. The severity clinic depends on type "cystic transmembrane regulatory protein" gene mutation. Although cases are diagnosed infancy or childhood, som...

conclusions the results demonstrated that the mortality rate was higher in cf patients with a positive family history, a consanguineous marriage, and residence in a rural area. therefore, demographic factors play an important role in the outcome of cystic fibrosis. unfortunately, these parameters, which can be managed easily and with low cost, have been overlooked. patients and methods this was...

to understand the role of religiousness/spirituality in coping in children with cystic fibrosis (cf). participants were a convenience sample of 23 patients with cf, ages 5 to 12 years and their parent(s) in an ambulatory cf clinic. the design was a focused ethnography including in-depth interviews with children and parent(s), children’s drawings and self-administered written parental questionna...