We report the first case of simultaneous, bilateral percutaneous management of multiple urinary cystine stones in a 7.6-kg, 9-month-old infant who presented with anuria. A stone-free state was successfully achieved.

The aim of this study was to investigate the utility of single-source dual-energy computed tomography (SS-DECT) composition analysis in characterizing different types of urinary stones and differentiating them from phleboliths. This study included 29 patients with urinary stones who were scheduled for surgery. All patients were scanned, first using single-energy computed tomography acquisition ...

Transl Androl Urol 2014;3(3):234 www.amepc.org/tau Cystinuria represents a relatively rare hereditary condition leading to impairment of the renal proximal tubule’s dibasic amino acid transporter. The only manifestation of this disease is calculi formation. Unlike other nephrolithiasis disease processes, cystine stone formation is due directly to supersaturation of an insoluble solute precipita...

PURPOSE Strontium has chemical similarity to calcium, which enables the replacement of calcium by strontium in biomineralization processes. Incorporating strontium into human bone and teeth has been studied extensively but little research has been performed of the incorporation of strontium into urinary calculi. We used synchrotron based x-ray fluorescence and x-ray absorption techniques to exa...

The treatment options for large renal calculi are controversial. We report on our experience with 65 treatments of renal calculi > 3 cm using extracorporeal shockwave lithotripsy (SWL) monotherapy. We stratified our results according to stone and collecting system surface areas (measured by computer image analyses), stone location, and stone type. The overall success rate of SWL monotherapy was...

Cystinuria is a rare inherited renal stone disease. Mutations in two genes SLC3A1 and SLC7A9 underlie this condition, encoding proteins that facilitate dibasic amino acid exchange which are expressed in the gut and the proximal tubule of the kidney. Genetic studies now allow precise genotyping of patients who may have both autosomal dominant and autosomal recessive patterns of disease. The diso...

Based on the 89 stones treated by ESWL therapy alone, the factors which influence the number of ESWL shots were analyzed. Stone volume was calculated by summing up the value "length x short axis" for each stone. The value correlated well with the number of shots needed to disintegrate the stone (p less than 0.01). The stones below the pelvis-ureteral junction needed twice shots compared with st...

Audience: Pediatrics; Nephrology Outpatient Clinic CYSTINURIA IS AN inherited, genetic condition that causes hyper-excretion of cystine and other dibasic amino acids (lysine, arginine, and ornithine) in the urine due to impaired transport in the proximal renal tubules. The low solubility of cystine leads to precipitation and the formation of renal stones. While rare, this condition accounts for...

The recognition of methionine as an important building stone of the protein molecule is one of the most significant advances in our knowledge of the chemistry of the biologically important sulfur compounds (1). Methionine has been shown to function similarly to cystine both for purposes of growth in rats fed a diet inadequate in its cystine content (2) and for the detoxication of monobromobense...

That the anuria was apparently painless yet due to bilateral obstruction of the ureters by calculi is noteworthy. Herring,4 in a study of 10 000 urinary calculi, found only 89 to contain cystine, of which about 700,, were composed of pure cystine, as in our case. Thus urinary tract calculi may be due to cystinuria even in a young child. Cystinuria5 is a recessive or incompletely recessive genet...