since the incidence of symptomatic congenital cytomegalovirus infection is low (~0.05%) and risk factors are not well defined, it is difficult to develop strategies for prevention. the aim of this study was to recognise the utility of specific immunoglobulin g avidity analysis for distinguishing primary infection from past/recurrent infection. sera from 50 women with cytomegalovirus specific im...

BACKGROUND Human cytomegalovirus infection is the most frequent viral complication in patients undergoing hematopoietic stem cell transplantation. We investigated the development of human cytomegalovirus-specific T cells in adult recipients of hematopoietic stem cell transplants. DESIGN AND METHODS From May 2003 through October 2006 a total of 45 patients were monitored for human cytomegalovi...

Recently, using polymerase chain reaction (PCR) technique, the DNA of cytomegalovirus was detected from depigmented white patches in patients with vitiligo. The reactivation of infection and occasional anti-CMV IgM circulating among patients infected by cytomegalovirus has been reported for years. We have studied 26 patients with clinical signs and symptoms of vitiligo, some of whom had a ...

background and aims: cytomegalovirus (cmv) is a member of herpesviruses. it is one of the most common cause of congenital and prenatal infections. cmv infection of pregnant women, especially in the first trimester may lead to congenital abnormalities in the newborns. the prevalence of cmv infection in developed countries is about 40% and in developing countries may be 100%. because there is no ...

results the mean ages in case and control groups were 60.8 ± 6.8 and 57.5 ± 11.5 years, respectively, with no significant difference (p = 0.09). thirty patients (54.5%) in case and 32 (58.2%) in control groups were male with no significant difference (p = 0.7). cmv-dna was present in 8 (14.5%) of the cases and 2 (4%) of the controls. cmv-dna was associated with higher risk of atherosclerosis (o...

OBJECTIVES Cytomegalovirus infection is an important cause of morbidity and mortality among recipients undergoing hematopoietic stem cell and solid-organ transplant. The risk of cytomegalovirus infection is high in cytomegalovirus-seronegative recipients of cytomegalovirus-seropositive organs (donor positive/recipient negative) and recipients with strong immunosuppressive status such as those r...

OBJECTIVE To determine the incidence of cytomegalovirus in the ejaculates of infertile men who were seropositive for IgG antibodies to cytomegalovirus. DESIGN Prospective study. PATIENT(S) We tested cytomegalovirus infection in the semen of men participating in an IVF-ET program. MAIN OUTCOME MEASURE(S) IgG and IgM antibodies to cytomegalovirus were measured in sera. We used polymerase ch...

BACKGROUND The identification of the best strategy to manage cytomegalovirus infection is hampered by uncertainties regarding the risk/benefit ratios of universal prophylaxis versus preemptive therapy, the impact of indirect cytomegalovirus effects and the associated costs. This study investigated the efficacy and safety of targeted preemptive therapy according to perceived risk of cytomegalovi...

Cytomegalovirus is an important cause of colonic disease in solid organ transplant recipients. Although several reports have shown that simultaneous infection with other pathogens may aggravate the course of cytomegalovirus colitis, to our knowledge, no case of colitis caused by simultaneous cytomegalovirus and Mycobacterium tuberculosis has been previously reported. We describe a case of hemor...

Evidence of cytomegalovirus infection has been sought in a consecutive series of patients requiring colonic resection for idiopathic inflammatory bowel disease confined to the colon. Colonic tissue was examined by light and electron microscopy for cytomegalovirus inclusion bodies and cytomegalovirus antigen was sought using an immunoperoxidase technique. Cytomegalovirus infection was identified...