نتایج جستجو برای: d76n

تعداد نتایج: 45  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Junko Kurokawa Lei Chen Robert S Kass

Beta-adrenergic receptor stimulation increases heart rate and shortens ventricular action-potential duration, the latter effect due in part to a cAMP-dependent increase in the slow outward potassium current (I(Ks)). Mutations in either KCNQ1 or KCNE1, the I(Ks) subunits, are associated with variants (LQT-1 and LQT-5) of the congenital long QT syndrome. We now show that cAMP-mediated functional ...

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