Interleukin-12 (IL-12) is a key immunoregulatory cytokine that promotes Th1 differentiation and cell-mediated immune responses. The transcription factor STAT4 (signal transducer and activator of transcription 4) is an important element in mediating IL-12 signals, as evidenced by the fact that STAT4(-/-) mice display impaired responsiveness to IL-12 and deficient Th1 differentiation. STAT4 is in...

We consider non-stationary time-series data for the size of the hidden economy and for tax-related prosecutions in New Zealand. The two series are found to be cointegrated, and there is strong evidence of Granger causality from prosecutions to hidden activity. There is no significant evidence of reverse causality. Author Contact: Professor David E. A. Giles, Department of Economics, University ...

Author Contact: David E. Giles, Dept. of Economics, University of Victoria, P.O. Box 1700, STN CSC, Victoria, B.C., Canada V8W 2Y2; e-mail: [email protected]; Phone: (250) 721-8540; FAX: (250) 721-6214 Abstract The Topp-Leone distribution is attractive for reliability studies as it has finite support and a bathtub-shaped hazard function. We compare some properties of the method of moments, maximum...

Author Contact: David E. Giles, Dept. of Economics, University of Victoria, P.O. Box 1700, STN CSC, Victoria, B.C., Canada V8W 2Y2; e-mail: [email protected]; Phone: (250) 721-8540; FAX: (250) 721-6214 Abstract By noting that the Hodrick-Prescott filter can be expressed as the solution to a particular regression problem, we are able to show how to construct confidence bands for the filtered time-s...

Contact author: David E. Giles, Dept. of Economics, University of Victoria, P.O. Box 1700, STN CSC, Victoria, B.C., Canada V8W 2Y2; e-mail: [email protected]; Phone: (250) 721-8540; FAX: (250) 721-6214 Abstract Testing for multivariate cointegration when the data exhibit structural breaks is a problem that is encountered frequently in empirical economic analysis. The standard tests must be modifie...

Cesar V Borlongan1,2†, Michael Chopp3, Gary K Steinberg4, Tonya M Bliss4, Yi Li3, Mei Lu3, David C Hess1 & Douglas Kondziolka5 †Author for correspondence 1Medical College of Georgia and Augusta VA Medical Center, Department of Neurology, 1120 15th Street Augusta, GA 30904, USA 2Tel.: +1 706 721 2145; Fax: +1 706 721 7619; E-mail: cborlongan@ mail.mcg.edu 3Henry Ford Hospital, Department of Neur...

A. Mohamad Ghazi,* Stephen Shuttleworth, Robert Simmons, S. John Paul and David H. Pashley Department of Geology, Georgia State University, Atlanta, GA 30303, USA. E-mail: [email protected]; Fax: 11 404 651 1376; Tel: 11 404 463 9556 New Wave Research Merchantek Products, 47613 Warm Springs Blvd, Fremont, CA 94539, USA. E-mail: [email protected] Department of Biology, Georgia State University, At...

Author Contact: David E., Dept. of Economics, University of Victoria, P.O. Box 1700, STN CSC, Victoria, B.C., Canada V8W 2Y2; e-mail: [email protected]; Voice: (250) 721-8540; FAX: (250) 721-6214 Abstract We examine the finite sample properties of the MLE for the Logit model with random covariates. We derive the second order bias and MSE function for the MLE in this model, and undertake some numer...