PURPOSE To evaluate the safety and performance of a second-generation device for CO2 laser-assisted sclerectomy surgery system in experimental models. MATERIALS AND METHODS Laser-assisted deep sclerectomy using a modified CO2 laser system (OT-134-"IOPtiMate"; IOPtima Ltd, Israel) was performed in 3 experimental models: enucleated pig eyes, human cadaver eyes, and live rabbit eyes. A half-thic...

PURPOSE To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) compared with classic nonpenetrating deep sclerectomy (NPDS) with implant in medically uncontrolled glaucoma patients. MATERIALS AND METHODS Patients who underwent primary filtration surgery with CO2 laser system at the time interval between July 2010 and April 2011 were identified, their medical files were rev...

We report a case of recurrent iris synechiae one year after Nd:YAG laser goniopuncture for deep sclerectomy enhancement in the only functional eye of a patient with end-stage glaucoma. The possible pathophysiology of this uncommon complication and laser treatment aspects are discussed.

Newer non-reabsorbing implants have been developed to maintain the hypotensor effect of nonpenetrating deep sclerectomy. In this article the authors discuss a new non-reabsorbing implant with 2-hydroxyethyl methacrylate (Esnoper®, AJL Ophthalmics, SA, Miñano, Alava, Spain), its design, technique of implantation and the available scientific evidence.

AIMS To study prospectively the success rate and complications of deep sclerectomy with collagen implant (DSCI), a new non-penetrating filtration procedure. METHODS Non-randomised prospective trial involving consecutive patients. 100 eyes of 100 patients with medically uncontrolled primary and secondary open angle glaucoma. A superficial scleral flap was raised and a deep sclerectomy was perf...

AIM To identify the value of using collagen implant in deep sclerectomy. METHODS A prospective randomised trial of 104 eyes (104 patients) with medically uncontrolled primary and secondary open angle glaucoma. All patients had deep sclerectomy (DS), half of them with and the other half without a collagen implant (CI) sutured in the scleral bed. The main outcome measures were intraocular press...