BACKGROUND CONTEXT Retrolisthesis is relatively rare but when present has been associated with increased back pain and impaired back function. Neither the prevalence of this condition in individuals with lumbar disc herniations nor its possible relation to preoperative back pain and dysfunction has been well studied. PURPOSE The purposes of this study were as follows: (1) to determine the pre...

Although success has been achieved with implantation of bone marrow mesenchymal stem cells (bMSCs) in degenerative discs, its full potential may not be achieved if the harsh environment of the degenerative disc remains. Axial distraction has been shown to increase hydration and nutrition. Combining both therapies may have a synergistic effect in reversing degenerative disc disease. In order to ...

introduction: due to limitations of current treatments for degenerative disc disease, arthroplastic methods to repair the diseased disc have been proposed. the artificial disc is a mobile implant for degenerative disc replacement that attempts to lessen the degeneration of the adjacent elements following interbody fusion procedures. because the success of artificial disc replacement depends on ...

background: a large proportion of patients presenting with lumbar disc disease are opium addicts in our region. it was, therefore, hypothesized that morphine might affect the intervertebral disc. we investigated the histological findings of morphine dependency on intervertebral discs in rat.   methods: forty nmri adult male rats (230-250 g) placed on ordinary diet and received aqueous solution ...

Low back pain as a result of degenerative disc disease imparts a large socioeconomic impact on the health care system. Traditional concepts for treatment of lumbar disc degeneration have aimed at symptomatic relief by limiting motion in the lumbar spine, but novel treatment strategies involving stem cells, growth factors, and gene therapy have the theoretical potential to prevent, slow, or even...

Background & Aim: Low back pain is broadly documented as one of the most widespread pathologies in the advanced domain. Although the reasons of low back pain are uncountable, it has been meaningfully related to intervertebral disc degeneration. Present therapies for Intervertebral Disc (IVD) degeneration such as physical therapy and spinal fusion reduce symptoms' severity, but do not treat the ...