BACKGROUND Jet nubulisers and metered dose inhalers are widely used to deliver aerosolised drugs to the lungs of intubated patients in adult intensive care units. Drug delivery using these systems has been shown to be inefficient and both forms of delivery have the potential to induce paradoxical bronchoconstriction in patients with reactive airways disease. METHODS Experiments were carried o...

Motion by releasing the oxygen from the cylinder. There was also a bag (as in Haldane's oxygen apparatus) Which served to keep the oxygen pressure from rising too high in the delivery tube. Thus the oxygen on its Way to the face kept the pump working, and this produced alternately a negative and positive pressure in the delivery tube provided the face-piece was closely applied to the face. This...

Complications may arise during enteral feeding that are usually related to the diameter and rigidity of the tube or the delivery, composition, and sterility of the feed uses. By using a soft, fine bore tube to deliver a sterile feed of known composition, by continuous infusion rather than as a bolus, most of these complications can be avoided.

The precise delivery of male to female gametes during reproduction in eukaryotes requires complex signal exchanges and a flawless communication between male and female tissues. In angiosperms, molecular mechanisms have recently been revealed that are crucial for the dialog between male (pollen tube) and female gametophytes required for successful sperm delivery. When pollen tubes reach the fema...

Several factors interact in influencing aerosol deposition during mechanical ventilation. Among these factors, the artificial airway is a significant barrier for aerosol deposition. Earlier studies overemphasized the impediments created by the artificial airway to aerosol delivery, because the aerosol generator was placed adjacent to the endotracheal tube or was connected to it. When the aeroso...

During the past 25 years, incremental gains in knowledge about aerosol delivery to mechanically ventilated patients had a major impact on patient care in this setting. The complex array of factors influencing aerosol delivery during mechanical ventilation made it difficult to elucidate the contribution of individual parameters to optimal aerosol delivery. Over the ensuing years, bench models ma...

in this study, using sound created by wheat grain passing through a pipe, wheat flow rate was measured. the developed device consists of a hopper, metering device, sound sensor, delivery tube, dc motor and power supply. several wheat mass flow rates were tested and the sound signal created by the passage of the grain through the discharge tube was measured and transferred to a computer using da...

Neural tube defects rank second to congenital heart disease as a major cause of congenital malformation. Recent developments in ultrasound have improved prenatal diagnosis. Due to anomaly scans at 18 weeks gestation and the availability of a genetic clinic, prenatal diagnosis of neural tube defects at the Royal Maternity Hospital was 91.2% during 1987-1989. However, only 50% of parents accept t...

Nerve guidance channels (NGCs) promote axonal regeneration after transection injury of the peripheral nerve or spinal cord, yet this regeneration is limited. To enhance regeneration further, we hypothesize that localized delivery of therapeutic molecules combined with the NGC is required. In an attempt to achieve such an NGC, we designed and synthesized a novel NGC in which protein-encapsulated...