Neurological complications are an important cause of morbidity in the postoperative period of cardiac surgery and its incidence reaches up to 75% of patients. An important cause of these events is the formation of microbubbles in the bloodstream during cardiopulmonary bypass. Integrative review was carried out on gaseous microemboli in cardiopulmonary bypass. This study analyzed studies with di...

Extravehicular activity (EVA) during spaceflight involves a significant decompression stress. Previous studies have shown an increase in the inhomogeneity of ventilation-perfusion ratio (VA/Q) after some underwater dives, presumably through the embolic effects of venous gas microemboli in the lung. Ground-based chamber studies simulating EVA have shown that venous gas microemboli occur in a lar...

BACKGROUND Localized singlet diradicals are in general quite short-lived intermediates in processes involving homolytic bond-cleavage and formation reactions. In the past decade, long-lived singlet diradicals have been reported in cyclic systems such as cyclobutane-1,3-diyls and cyclopentane-1,3-diyls. Experimental investigation of the chemistry of singlet diradicals has become possible. The pr...

This paper presents a mathematical model of a semi-closed anesthesia breathing circuit. The model comprises four perfect-mixing compartments (corresponding to the lung, the reservoir bag, and the two absorber cannisters), together with four tubes through which gas flows without mixing (corresponding to the inspiratory tube, the expiratory tube, the arm leading to the reservoir bag, and the anat...

We report the attempted development of a photoredox-catalyzed α-C–H alkylation reaction aliphatic amine derivatives, using N-tosylhydrazones as radical alkylating partners. The original intention was to intercept α-aminoalkyl intermediates with N-tosylhydrazones, followed by expulsion sulfonyl β-scission generate N-H diazene species. Facile denitrogenation these would remove all traces hydrazon...