نتایج جستجو برای: density qpcr array

تعداد نتایج: 548139  

Journal: :iranian journal of astronomy and astrophysics 2014
gohar rastegarzadeh sahar khoshabadi

simulation of gamma and hadron showers in the energy range 100gev- 25tev has been carried out. for a big ideal cherenkov light array, characteristics of lateral distribution of cherenkov photon density have been studied. results from this ideal detector are compared with those simulated for a real tunka- like array to investigate experimental potential of using existence of a hump in lateral di...

Bazrgar M, Borjian Boroujeni P, Borna S Gourabi H Karimpour-fard A Movaghar B Rezazadeh Valojerdi M Vermeesch JR Voet T Zamani Esteki M,

Background: Origin of midlife copy number variations (CNVs) between tissues in non-genetic diseases is unknown. Such genomic differences caused by post-zygotic events. They might either happen during the life or due to prevalent mosaicism in preimplantation stage. We aim to explore fetal mosaicism and its origins. Materials and Methods: Two apparently normal fetuses were achieved following the ...

Gohar Rastegarzadeh Sahar Khoshabadi

Simulation of gamma and hadron showers in the energy range 100GeV- 25TeV has been carried out. For a big ideal Cherenkov light array, characteristics of lateral distribution of Cherenkov photon density have been studied. Results from this ideal detector are compared with those simulated for a real TUNKA- like array to investigate experimental potential of using existence of a hump in lateral di...

2014
J F Gritzfeld A J H Cremers G Ferwerda D M Ferreira A Kadioglu P W M Hermans S B Gordon

The density and duration of pneumococcal carriage are considered to affect the likelihood of transmission and invasive disease. Because of its importance in both spreading and causing disease, carriage has been suggested as an endpoint in future vaccine studies. Culture is the current gold standard for detection, but may not be sensitive enough to detect changes at low density. Healthy adult vo...

2015
Rosangela Ferese Nicola Modugno Rosa Campopiano Marco Santilli Stefania Zampatti Emiliano Giardina Annamaria Nardone Diana Postorivo Francesco Fornai Giuseppe Novelli Edoardo Romoli Stefano Ruggieri Stefano Gambardella

Background. Parkinson's disease (PD) is mostly characterized by alpha-synuclein (SNCA) aggregation and loss of nigrostriatal dopamine-containing neurons. In this study a novel SNCA multiplication is described in two siblings affected by severe parkinsonism featuring early onset dyskinesia, psychiatric symptoms, and cognitive deterioration. Methods. SNCA dosage was performed using High-Density C...

2017
Iñaki Rodriguez-Agirretxe Iker Garcia Javier Soria Tatiana Maria Suarez Arantxa Acera

Excessive subconjunctival scarring is the main reason of failure of glaucoma filtration surgery. We analyzed conjunctival and systemic gene expression patterns after non penetrating deep sclerectomy (NPDS). To find expression patterns related to surgical failure and their correlation with the clinical outcomes. This study consisted of two consecutive stages. The first was a prospective analysis...

Journal: :The Pediatric infectious disease journal 2016
Adam Finn Begonia Morales-Aza Paulina Sikora Jessica Giles Ryan Lethem Matko Marlais Valtyr Thors Andrew J Pollard Saul Faust Paul Heath Ian Vipond Muriel Ferreira Peter Muir Luís Januário Fernanda Rodrigues

BACKGROUND Improved understanding of Neisseria meningitidis (Nm) carriage biology and better methods for detection and quantification would facilitate studies of potential impact of new vaccines on colonization and transmission in adolescents. METHODS We performed plate cultures on 107 oropharyngeal swabs stored frozen in skim milk tryptone glucose glycerol (STGG) broth and previously positiv...

2009
Etienne Rouleau Cédrick Lefol Violaine Bourdon Florence Coulet Tetsuro Noguchi Florent Soubrier Ivan Bièche Sylviane Olschwang Hagay Sobol Rosette Lidereau

Several techniques have been developed to screen mismatch repair (MMR) genes for deleterious mutations. Until now, two different techniques were required to screen for both point mutations and large rearrangements. For the first time, we propose a new approach, called ‘‘quantitative PCR (qPCR) high-resolution melting (HRM) curve analysis (qPCR-HRM),’’ which combines qPCR and HRM to obtain a rap...

2016
Bettina Schlick Petra Massoner Angelika Lueking Pornpimol Charoentong Mirjam Blattner Georg Schaefer Klaus Marquart Carmen Theek Peter Amersdorfer Dirk Zielinski Matthias Kirchner Zlatko Trajanoski Mark A. Rubin Stefan Müllner Peter Schulz-Knappe Helmut Klocker Aamir Ahmed

BACKGROUND Chronic inflammation is frequently observed on histological analysis of malignant and non-malignant prostate specimens. It is a suspected supporting factor for prostate diseases and their progression and a main cause of false positive PSA tests in cancer screening. We hypothesized that inflammation induces autoantibodies, which may be useful biomarkers. We aimed to identify and valid...

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