OBJECTIVE In the present study, it is describe the phenotypical analysis and the mutational screening, for genes PAX9 and MSX1, of six families affected by severe forms of tooth agenesis associated with other dental anomalies and systemic entities. STUDY DESIGN Six families affected by severe tooth agenesis associated with other dental anomalies and systemic entities were included. Oral explo...

Non-syndromic permanent canine agenesis, or combined with agenesis, or developmental absence of other tooth types, has occasionally been described in the literature, but isolated forms are rarely observed. The purpose of the present retrospective radiographic study was to provide data on the prevalence and distribution of permanent canine agenesis in the Hungarian population. Dental panoramic t...

Tooth agenesis is the most common of all dental developmental disorders. The mandibular second premolars are the teeth most commonly found missing (2.2 to 4.1%) after the third molars. There are more studies on tooth agenesis than the other malformations but yet they are limited. This article reviews the studies related to agenesis of mandibular second premolars and the underlying mechanisms be...

We describe a female patient with a midline syndrome. The patient presents agenesis of the corpus callosum, encephalocele, iris coloboma, hypertelorism, submucosal cleft palate and dental anomalies. Despite being very characteristic, her phenotypical traits do not coincide exactly with those reported to date in the literature. The karyotype and the molecular cytogenetic study do not show mutati...

Objectives:The aim of this study is to find some genetic aspects of dental agenesis and, in particular, to analyze mutations in the MSX1 and PAX9 genes in individuals with non-syndromic dental agenesis. The aim is to enhance our understanding of the genetic basis of these anomalies and to provide an epidemiological overview regarding the incidence of agenesis in the population, by innovative, m...

PURPOSE In adults, sphenoid sinus agenesis is an extremely rare anomaly. The objective of this study was to investigate the prevalence of sphenoid sinus hypoplasia and agenesis using dental volumetric computed tomography (DVCT) in a population of Turkish individuals. MATERIALS AND METHODS DVCT scans in the axial, coronal and sagittal planes of the sphenoid sinus of 384 patients were examined ...

INTRODUCTION Tooth agenesis is a phenomenon that occurs relatively commonly. The incidence of the missing teeth presented in the previous reports varies according to the studied population. OBJECTIVE The aim of this study was to find the prevalence of tooth agenesis in a population group in Bucharest. METHODS AND RESULTS The prevalence and distribution of dental agenesis was determined in a...

PURPOSE The aims of this article are to critique the available literature on dental implants in patients with ectodermal dysplasia (ED) syndrome and tooth agenesis, review the outcomes of implant therapy in these patients, and provide recommendations on the timing of implant placement for these patients. MATERIALS AND METHODS Searches were performed using Medline, Embase, All EBM Reviews, and...

While understanding somatic variability among wild primates can provide insight into natural patterns of developmental plasticity, published data for living populations are rare. Here we provide such information for two distinct wild populations of Lemur catta. Variants observed include microtia, athelia, and female virilization. Dental variants observed include individuals with supernumerary t...

The phenomenon of congenitally missing teeth has been described with different names: hypodontia, oligodontia, anodontia, congenitally missing teeth and dental agenesis. The present paper reports familial hypodontia, involving two siblings from a single family. Case I reported the absence of 18, 12, 22 and 31 teeth whereas case II reported the absence of 31 and 41. On the evaluation of the two ...