Odontoblasts produce most of the extracellular matrix (ECM) components found in dentin and implicated in dentin mineralization. Major differences in the pulp ECM explain why pulp is normally a non-mineralized tissue. In vitro or in vivo, some dentin ECM molecules act as crystal nucleators and contribute to crystal growth, whereas others are mineralization inhibitors. After treatment of caries l...

The diameter and density of coronal dentinal tubules were assessed in non-erupted human deciduous incisors. Using liquid nitrogen, frozen samples were fractured in longitudinal and oblique directions and observed by means of a Jeol JSM-6100 scanning electron microscope. It was observed that the diameter of dentinal tubules ranged from 0.50 to 1.94 micrometers and increased significantly from th...

BACKGROUND Dentinal hypersensitivity is a very common complaint of patients undergoing crown and bridge restorations on vital teeth. Of the many desensitizing agents used to counter this issue, desensitizing laser treatment is emerging as one of the most successful treatment modality. However, the dentinal changes brought about by the desensitizing laser application could affect the bond streng...

The purpose of this study was to investigate dentin-bridge formation in teeth following the transplantation of dental pulp-derived cells seeded on hydroxyapatite/tricalcium phosphate (HA/TCP) scaffolds. The dental pulp tissues were removed from the extracted first molar teeth of miniature pigs and single cell populations were subcultured. Second-passage cells that had alkaline phosphatase activ...

The purpose of this review was to get significant experimental data about the acid etching technique upon pulpo-dentinal complex highlighting aspects such as pulpal biology and dentinal permeability. Studies since early 70's, going 80's 90's show value retention well need protective bases lower toxic effects etching.

The effects of dietary sucrose and systemic glucocorticoid treatment on the response of the pulpodentinal complex to dental caries were examined in an experimental rat model. The possible role of dentinal caries on dentin formation was also examined. After 5-6 weeks of a dietary and/or medication period, the areas of dentin formation and dentinal caries were quantified in the molars of growing ...

It was in the 1980s when the association between root-filling procedures and dentinal microcracks was made. Nowadays, root-originating microcracks, also known as dentinal defects, are recognized as a possible precursor that is part of the longitudinal process of root-originating fractures. The presence of dentinal defects has been shown to significantly decrease the outcome through a periapical...

INTRODUCTION This clinical study evaluates the effect of ultrasonic root-end preparations on dentinal defect creation and propagation. METHODS Eighty-four teeth were treated with periapical microsurgery using a modern microsurgical protocol in a private practice setting. The root apices were resected and inspected for dentinal defects with a surgical operating microscope and a 0.8-mm diameter...

BACKGROUND This study aims to evaluate the frequency of dentinal defects after root canal preparation with the ProTaper NEXT, K3XF and WaveOne GOLD systems using microcomputed tomography. METHODS Sixty permanent mandibular incisors with a single canal were selected. Inspection of the teeth was performed under a stereomicroscope (15x) to observe the presence of pre-existing cracks and fracture...