The thionamide drugs, i.e. carbimazole and its metabolite methimazole (MMI), andpropylthiouracil (PTU) have extensively been used in the management of various forms ofhyperthyroidism over the past eight decades. This review aims to summarize different aspectsof these outstanding medications. Thionamides have shown their own acceptable efficacy andeven safety profiles in ...

To explain cognitive and memory difficulties observed in some familial hemiplegic migraine (FHM) patients, we examined hippocampal neurotransmission and plasticity in knock-in mice expressing the FHM type 1 (FHM1) R192Q gain-of function mutation in the CACNA1A gene that encodes the α1A subunit of neuronal CaV2.1 channels. We determined stimulus intensity-response curves for anterior commissure-...

The thionamide drugs, i.e. carbimazole and its metabolite methimazole (MMI), andpropylthiouracil (PTU) have extensively been used in the management of various forms ofhyperthyroidism over the past eight decades. This review aims to summarize different aspectsof these outstanding medications. Thionamides have shown their own acceptable efficacy andeven safety profiles in ...

due to frequent threats of israel by iraq and its approach to attain nuclearweapons, israel destroyed iraq’s atomic installations in 1982 .during 1990szionist regime and its followers asked u.s to resolve once and remove iraqthreats over israel .in 2003 after iraq occupation zionist regime took irannuclear activities under control closely and approached to syria and turkey .israel tries to put ...

from long time ago the shortage of finance in business practices was one of the striking problems for traders and thus there have always been endeavors to find a solution to it. one of the ways put forward was using the stocks stored in warehouses as security for loans. taking advantage of a descriptive method, this paper describes field-warehousing as a means of raising cash funds and the regu...

abstract      uncertainty is one of the general rules of the law of contract that is discussed from different aspects under islamic and iranian law. however, despite the long history of the subject and its importance, there are still ambiguities about its application in contracts especially the new ones. this article succinctly examines the meaning, scope and application of gharar (uncertainty)...