نتایج جستجو برای: dextran microspheres

تعداد نتایج: 21170  

Maryam Eskandari Mohsen Tafaghodi,

Objective(s) The immunoadjuvant potential of cross-linked dextran microspheres (CDM) as absorption enhancer and Quillaja saponins (QS) as immunomodulator adjuvant was evaluated. Materials and Methods CDM loaded or tetanus-mixed toxoid (TT) or Quillaja saponin (QS) were nasally administered to rabbits in dry powder form, three times in 2 weeks interval and serum IgG and nasal lavage sIgA tite...

Journal: :Environmental science & technology 2005
Michael B Salerno Sam Rothstein Chisomaga Nwachukwu Haithem Shelbi Darrell Velegol Bruce E Logan

This study examines differences between chemisorbed and physisorbed biomolecules on bacterial adhesion to both hydrophobic and hydrophilic surfaces that are biologically nonspecific. Bacteria-sized latex microspheres were used as a simplified model in order to study these factors that affect microbial adhesion. Two biomolecules (protein A, poly-D-lysine) were covalently bound to microspheres in...

1999
Terri A. Camesano Kenneth M. Unice Bruce E. Logan

A model accounting for the dynamics of colloid deposition in porous media was developed and applied to systems containing similarly charged particles and collectors. Colloid breakthrough and intracolumn retention data confirmed that blocking reduced overall colloidal adhesion to soil. The surface coverage at which blocking occurred varied for the type of colloid, as shown by changes in the clea...

2010
Thomas Schlorf Manuela Meincke Elke Kossel Claus-Christian Glüer Olav Jansen Rolf Mentlein

Superparamagnetic iron-oxide particles (SPIO) are used in different ways as contrast agents for magnetic resonance imaging (MRI): Particles with high nonspecific uptake are required for unspecific labeling of phagocytic cells whereas those that target specific molecules need to have very low unspecific cellular uptake. We compared iron-oxide particles with different core materials (magnetite, m...

Journal: :Biological & pharmaceutical bulletin 2001
A García-Arieta S Torrado-Santiago L Goya J J Torrado

The aim of this work is to describe and characterize a new spray-drying procedure for the production of nasal powders as an alternative to the conventional freeze-drying method. Cyanocobalamin was chosen as the active ingredient and loaded into five different nonsoluble vehicles with high water absorption ability. Then these hydrated particles were suspended in methylene chloride and spray-drie...

Journal: :Hearing research 1988
A L Nuttall E Hultcrantz H C Larsen C Angelborg

Guinea pig cochlear blood flow was measured before and after systemic normovolemic hemodilution with high molecular weight dextran. Absolute determinations of blood flow (in the cochlea, brain, kidney and lung) were accomplished by use of radioactive-labeled (85Sr or 141Ce) microspheres. Relative measurements of the cochlear blood flow changes were made simultaneously by the use of a laser Dopp...

2012
Guang Liu Xiaoyun Hong Mier Jiang Weien Yuan

BACKGROUND The main treatments for cancers are still chemotherapy and radiotherapy for intermediate-stage cancer and terminal cancer. However, the therapeutic methods often result in a decreased neutrophilic granulocyte count and other side effects. In this study, in order to improve the neutrophilic granulocyte levels in the blood after radiotherapy and chemotherapy, we developed a sustained-r...

Journal: :iranian journal of pharmaceutical research 0
mitra jelvehgari department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. drug applied reseach center, tabriz university of medical sciences, tabriz, iran. davoud hassanzadeh department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. drug applied research center, tabriz university of medical sciences, tabriz, iran. farhad kiafar department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. badir delf loveymi department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. sara amiri department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran.

the objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (ma) using two polymers with different characteristics as ethylcellulose (ec) and/or cellulose acetate phthalate (cap). microspheres were prepared by the modified emulsion solvent evaporation (mese). the effect of drug-polymer interaction was studied for each of microspheres. important param...

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