background and objective: diabetes mellitus is common endocrine disease cause learning and memory impairment. this study was done to evaluate the effect of quercetin on learning and memory in stz-induced diabetic rats was investigated. methods: in this experimental study, 40 male wistar rats were randomly allocated into five groups: control, quercetin - treated control, diabetic and quercetin -...

objectives the aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (rbcs) indices in diabetic rats. materials and methods peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and normal male and female rats and hematological parameters were measured. results the mean number of whi...

introduction: it seems that improvement in care and new treatment and screening methods along with better control of diabetes mellitus (dm) has led to a change in incidence of diabetic complications, especially diabetic retinopathy .this study was performed to assess the 4 years incidence rate of diabetic retinopathy in patients with type ii diabetes and factors affecting its progression. metho...

diabetic macular edema (dme) is a leading cause of vision loss in the working-age population worldwide. numerous early studies suggest an important role for intravitreal anti-vegf agents such as bevacizumab in the management of dme. we reviewed manuscripts that had investigated pharmacokinetic, efficacy, safety, dose and frequency of intravitreal bevacizumab (ivb) injections as well as effect o...

conclusions we identified a strong association between the t allele of il6r gene polymorphisms (rs2229238, rs4845625) and the risk of t2d in a protective role and as a risk factor, respectively. we also found different bmi and hdl values between the patient group and the control group, respectively in compare genotypes (ct+tt vs. cc). further studies on various ethnicities are necessary to veri...

extractdefective corneas are the leading cause of blindness world wide and the second leading cause, after diabetic retinopathy,of blindness in the united state , afflicting 30000 americans each year. happily, nearly 95 percent of those who have corneal transplantations( in 1985 they numbered,26300) regain their sight. the cornea is a transparent, a vascular, dim-sized tissue continious with th...

objective: quality of life (qol) is an intellectual concept consisting of positive and negative aspects of an individual’s life and indeed it demonstrates the method by which a person perceives the health condition as well as the other aspects of his/her life and reacts to them. currently, assessment of qol is more considered because of the increased prevalence of chronic diseases. so, the curr...

abstract   introduction: diabetes mellitus accompanies with disturbances in learning, memory, and cognitive skills in the human society and experimental animals. considering the beneficial antidiabetic potential of nigella sativum (ns ), this research study was conducted to evaluate the effect of chronic consumption of ns on learning and memory in diabetic rats using passive avoidance and y-maz...

clinical assessment of distal symmetric polyneuropathy (dpn) involves the evaluation of symptoms and signs. although there are numerous tools to evaluate dpn, there is still a need to determine the most sensitive, specific, and accurate tests to detect dpn in a busy outpatient clinical setting. a total of 107 patients with type 2 diabetes were examined using michigan neuropathy screening instru...

we have studied the ulcerogenic effect of indomethacin in stretozocin. induced diabetic rats. streptozocin (65 mg kg-1) was injected intraperitoneally to male wistar rats. the blood glucose concentration was determined continuously. blood glucose level increased significantly (p<0.001) after 30 days. gastric erosions were induced by intraperitoneal injection of indomethacin (50 mg kg-1) in fast...