α,β-Unsaturated N,N-dialkyl hydrazones undergo a mild [2 + 2] cycloaddition to allenamides when treated with a suitable gold catalyst. The method, which represents the first application of N,N-dialkyl hydrazones in gold catalysis, is compatible with a wide variety of substituents at the alkenyl moiety of the hydrazone component, proceeds with excellent levels of regio- and diastereoselectivity,...

The formation of striped phases of dialkyl disulfides on Au(111) and graphite has been monitored by scanning tunneling microscopy (STM). STM imaging clearly exhibits the formation of striped phases having corrugation periodicities that are nearly consistent with the molecular length of alkanethiolate moieties formed after the S-S bond cleavage of dialkyl disulfide on a gold surface. This is the...

Ionic liquids such as 1,3-dialkylimidazolium salts make excellent catalysts and solvents for synthesis of dialkyl 2-(dialkoxyphosphoryl)-3-(1-oxo-1-H-phthalazin-2-yl)succinates from 2H-phthalazin-1-one, dialkyl acetylenedicarboxylates, and trialkyl phosphites. Under similar conditions, triphenyl phosphite led to dialkyl 2-(diphenoxyphosphoryl)-3-(1-oxo-1-H-phthalazin-2-yl)succinates. The ionic ...

Recent single-molecule experiments indicated that thioethers (dialkyl sulfides) on gold surfaces act as thermallyor mechanically activated molecular rotors, although the mechanisms for these phenomena are not yet clearly understood. Here we present theoretical and experimental investigations of the rotational dynamics of these thioether molecules. Single-molecule studies utilizing low-temperatu...

We describe convenient preparations of N,N′-dialkyl-1,3-propanedialdiminium chlorides, N,N′-dialkyl-1,3-propanedialdimines, and lithium N,N′-dialkyl-1,3-propanedialdiminates in which the alkyl groups are methyl, ethyl, isopropyl, or tert-butyl. For dialdiminium salts, N2C3 backbone is always trans-s-trans configuration. Three isomers present solution except for tert-butyl compound, only two pre...

The capacities to inhibit coumarin 7-hydroxylase activity of human cytochrome P450 2A6 (CYP2A6) by organosulfur compounds were evaluated. Five dialkyl sulfides and five dialkyl disulfides, with alkyl chains from methyl to amyl, were examined. In addition to these chemicals, diallyl sulfide, diallyl disulfide, allyl methyl sulfide, allyl n-propyl sulfide, allyl phenyl sulfide, diphenyl sulfide, ...

A comparison of the (13)C nuclear magnetic resonance chemical shifts of some 15,16-dialkyl-15,16-dihydropyrenes with the corresponding 15,16-dialkyl-2,7,15,16-tetrahydropyrenes provides a measure of the effect of ring current on carbon-13 chemical shifts in which other effects may be expected to be negligibly small. The general conclusion is that the absolute magnitude of the ring-current effec...

Iron(II) and iron(III) salts catalyze the oxidative alpha-phosphonation of N,N-dimethylanilines with dialkyl H-phosphonates in the presence of tert-butylhydroperoxide.