نتایج جستجو برای: differentiated thyroid cancer
تعداد نتایج: 1022220 فیلتر نتایج به سال:
BACKGROUND Increased body mass index is related to the incidence of thyroid cancer. However, the presentation and therapeutic outcomes of different thyroid cancers and type 2 diabetes mellitus (DM) have not been studied. This study investigated the effect of type 2 DM on the clinical presentations and therapeutic outcome of well-differentiated thyroid cancer. METHODS AND FINDINGS A retrospect...
BACKGROUND Little is known about the causes of thyroid cancer, but insulin-like growth factor-I (IGF-I) might play an important role in its development due to its mitogenic and antiapoptotic properties. METHODS This study prospectively investigated the association between serum IGF-I concentrations and risk of differentiated thyroid carcinoma in a case-control study nested within the European...
Anaplastic thyroid cancer (ATC) is one of the most lethal human malignancies, but its genetic drivers remain little understood. In this study, we report losses in expression of the miRNA miR30a, which is downregulated in ATC compared with differentiated thyroid cancer and normal tissue. miR30a downregulation was associated with advanced differentiated thyroid cancer and higher mortality. Mechan...
The article reviews the controversial area of poorly differentiated thyroid carcinoma. Consensus criteria that define poorly differentiated thyroid carcinoma have been published in 2007. According to these, poorly differentiated thyroid carcinoma is a distinct histotype and the term "poorly differentiated" should not be used as a synonym for high-grade thyroid cancer. Data in the literature sho...
BACKGROUND A cDNA microarray analysis of anaplastic thyroid cancer cell lines (ACL) was recently performed and the down-regulation of phosphatidylethanolamine-binding protein (PBP) [RAF kinase inhibitor protein (RKIP)] in ACL compared to normal thyroid tissues was identified. MATERIALS AND METHODS The expression levels of PBP in primary anaplastic and papillary thyroid cancer, thyroid cancer ...
The contemporary management of well-differentiated thyroid cancer requires a multidisciplinary approach involving primary care physicians, endocrinologists, surgeons, pathologists, nuclear medicine specialists, and sometimes radiologists and oncologists for diagnosis, treatment, and long-term surveillance. Well-differentiated thyroid carcinoma includes papillary and follicular thyroid carcinoma...
The incidence of thyroid cancer is growing at a rapid rate, with the majority of cases being differentiated thyroid cancers. Although a significant number of patients with localized disease are cured, a paucity of effective therapies currently exists for patients with recurrent and/or metastatic disease. The translational bridging of critical biologic insights into the pathogenesis of thyroid c...
introduction:differentiated thyroid carcinoma (dtc) follow-up after thyroidectomy and radioiodine-ablation is performed mainly by thyroglobulin (tg), diagnostic iodine-131 whole body scan (dxwbs) and sonography. some patients with undetectable tg have thyroid-bed uptake after ablation in whom decision making regarding the need for retreatment is still controversial. methods: in this study, we e...
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