Pure tubulin dimer, purified by phosphecellulose chromatography to remove microtubule associated proteins, can be assembled into microtubules in the presence of dimethyl sulfoxide. The surfaces of such microtubules are devoid of filamentous material. The reaction is rapid and strongly dependent on protein concentration. No microtubule formation occurs from the purified tubulin when dimethyl sul...

Clonal lines of Rauscher erythroleukemia cells exhibited selective responses to two inducers of differentiation, erythropoietin and dimethyl sulfoxide. There were substantial quantitiative differences between clones that reponded to both inducers. Several clones differentiated only in response to erythropoietin. Erythropoietin stimulated cell proliferation and differentiation whereas dimethyl s...

The structure of the title salt, 2C(2)H(7)OS(+)·Br(6)Te(2-)·2C(2)H(6)OS, displays O-H⋯O hydrogen bonding between one protonated dimethyl sulfoxide mol-ecule and a neighboring dimethyl sulfoxide mol-ecule, and an octa-hedral geometry for the Te atom; the latter is situated on a center of inversion.

Extravasation of Adriamycin during i.v. infusion can cause serious local complications. We have used a rat skin model to study the protection afforded by dimethyl sulfoxide and alpha-tocopherol (vitamin E) against Adriamycin-induced skin necrosis. Topical daily application of 1 ml dimethyl sulfoxide for 2 days produced a small decrease in ulcer diameter of up to 11% at 2 weeks. Topical daily ap...

The Friend virus-infected murine erythroleukemia cell can be induced to differentiate along erythroid cells in culture with various compounds, including dimethyl sulfoxide. DNA from murine erythroleukemia cells cultured with dimethyl sulfoxide shows a decrease in sedimenta tion rate in alkaline sucrose gradients after alkali lysis of the cells. These changes can be detected as early as 27 hr af...

background: dosimetry is a fundamental part of the radiation processing industry. aqueous inorganic dosimeters have been used for gamma radiation dosimetry such as standard ferrous sulfate dosimeter. the purpose of this study was to investigate the effect of gamma radiation on the diethyl fumarate def in dimethyl sulfoxide dmso solution and its possible use in chemical dosimetry. materials and ...

The dimerization of acetoacetamide easily proceeds at room temperature in a dimethyl sulfoxide solution to afford 5-carbamoyl-4,6-dimethyl-2-pyridone.