نتایج جستجو برای: discover
تعداد نتایج: 35600 فیلتر نتایج به سال:
Some of the most extreme marine habitats known are the Mediterranean deep hypersaline anoxic basins (DHABs; water depth ∼3500 m). Brines of DHABs are nearly saturated with salt, leading many to suspect they are uninhabitable for eukaryotes. While diverse bacterial and protistan communities are reported from some DHAB water-column haloclines and brines, the existence and activity of benthic DHAB...
The phenotype-based drug discovery (PDD) approach is re-emerging as an alternative platform for drug discovery. This review provides an overview of the various model systems and technical advances in imaging and image analyses that strengthen the PDD platform. In PDD screens, compounds of therapeutic value are identified based on the phenotypic perturbations produced irrespective of target(s) o...
Between 1822 and the late 1830s a highly personal priority dispute was fought between the celebrated surgeon and anatomist Sir Charles Bell and his ex-student Herbert Mayo. The dispute was over the motor and sensory functions of the Vth and VIIth cranial nerves. Over the course of the 1820s and the 1830s, the competing claims of Bell and Mayo were presented in newspapers, journals, and textbook...
This report describes investigations into DISCOVER, a modern software development and maintenance environment. The study is guided by a framework for classifying program understanding tools that is based on a description of the canonical activities that are characteristic of the reverse engineering process. Implications of this work for advanced practitioners, researchers and tool developers, a...
در این تحقیق نرم افزار تحت وب discover معرفی شده است که می تواند جفت های باقی مانده ای را که در صورت جهش به سیستئین، پیوند دی سولفید ایجاد می کنند و موجب بهبود پایداری پروتئین می شوند، پیش بینی کند. پیش بینی بر پایه شرایط ساختاری باقی مانده ها و تفاوت ویژگی های فیزیکی و شیمیایی اسیدهای آمینه نسبت به سیستئین انجام شده است. برای ارزیابی شرایط ساختاری از دسترس پذیری به سطح و انعطاف پذیری استفاده م...
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