In this study, a novel mesoporous silica nanoparticles drug carrier contributes to improving the solubility, dissolution, and the oral bioavailability of apigenin (AP). The apigenin of solid dispersion of mesoporous silica nanoparticles (AP-MSN) was prepared by physical absorption method and also, in-vitro drug release and in-vivo bioavailability performance were evaluated. Based on its solubil...

an experimental study has been made of the hydrodynamics of a stage mixer-settler to obtain appropriate design information. in this paper several tests were done according to full factorial design of experiments with high reliability, since each test recurs seven times and the results of  them are very close to each other(p=1bar and t=25 °c). sauter diameter in each test is determined with phot...

Probabilistic modeling is cyclical: we specify a model, infer its posterior, and evaluate its performance. Evaluation drives the cycle, as we revise our model based on how it performs. This requires a metric. Traditionally, predictive accuracy prevails. Yet, predictive accuracy does not tell the whole story. We propose to evaluate a model through posterior dispersion. The idea is to analyze how...

The optical rotatory dispersion of five individual specimens of Bence-Jones proteins was investigated, including the far ultraviolet spectral zone. The Mo5tt constants (bo) were determined, and either low positive or low negative values were found. The rotatory dispersion curves of all specimens had flat negative minima at 220 to 235 rnp and positive maxima at 204 to 212 rnp. Denaturation with ...

An analytical solution for the transient two-dimensional atmospheric pollutant dispersion problem is presented. The approach used in this problem utilizes the double GITT (Generalized Integral Transform Technique), the Laplace Transform and the matrix diagonalization. Furthermore, mathematical filters are used due to the existence of non-homogeneous boundary conditions. The results we obtained ...

A [0, m]-space is a linear space with the following property: For any point-line pair (x, G) there are at most m lines through x which are coplanar with G and which have no point in common with G. For every [0, m]-space (M, 90l) we define an order o r d M in a natural way. For dimM~>3 and o r d M ~ > 3 m + 2 , every [0, m]-space (M, 991) can be embedded in a projective space (P, £) with dim P =...

Whtle many people report interruptions from problem-solking to be beneficial for the creative process (‘incubation’). experimental demonstration of the phenomenon has been difficult. Factors that might lead to incubation effects are discussed and implemented in a study in which SO university students solved u-ord-association problems under continuous work or interrupted condttions. The interrup...

Background Anthracyclines are important components of many chemotherapeutic protocols. The present study aimed to evaluate the repolarization changes in electrocardiography (ECG) which may predict drug induced arrhythmia. Materials and Methods In this cross-sectional study, the recorded ECGs were assessed for QT dispersion (QTd), QT corrected dispersion (QTcd), T peak to Tend dispersion (TPe...

In this study, a novel mesoporous silica nanoparticles drug carrier contributes to improving the solubility, dissolution, and the oral bioavailability of apigenin (AP). The apigenin of solid dispersion of mesoporous silica nanoparticles (AP-MSN) was prepared by physical absorption method and also, in-vitro drug release and in-vivo bioavailability performance were evaluated. Based on its solubil...

This article presents the approach and current findings of the EO2HEAVEN project, in particular from the Saxony Case Study. The aim of the Case Study is the conceptual design of a Spatial Information Infrastructure for better understanding the complex relationship between ambient air quality and its influence on the human health. This includes air quality modelling and a statistical analysis of...