Objective: Iron is an element, which found in the structure of antioxidant enzymes and has important role inactivation reactive oxygen species. Disruption oxidant-antioxidant balance may be playing a pathogenesis iron deficiency anemia (IDA). Dynamic thiol-disulfide homeostasis (DTDH) serum ischemia-modified albumin (IMA) levels are indicators pro-oxidant/antioxidant status. In this study, we a...

carbon disulfide is used predominantly in the manufacture. it has affects the nervous system. in this study, the applicability of spme as a passive sampler for determination of carbon disulphide in air was studied. effect of sampler and environmental parameters on uptake of carbon disulphide was studied as well. four fibers were tested to select the best sampler for determine carbon disulfide i...

PLANTS ARE UNIQUE AMONG EUKARYOTES IN HAVING EVOLVED ORGANELLES the protein storage vacuole, protein body, and chloroplast. Disulfide transfer pathways that function in the endoplasmic reticulum (ER) and chloroplasts of plants play critical roles in the development of protein storage organelles and the biogenesis of chloroplasts, respectively. Disulfide bond formation requires the cooperative f...

Objective: To determine serum thiol/disulfide homeostasis in panic disorder (PD). Methods: Serum native thiol, total thiol, and disulfide levels were measured in the patients with 40 PD patients and 40 healthy subjects. Serum native thiol, total thiol, and disulfide levels were measured with a novel colorimetric, automated method. The thiol-disulfide ratio was also calculated. Results: The nati...

Protein disulfide isomerases (PDIs), a family of thiol-disulfide oxidoreductases that are ubiquitous in all eukaryotes, are the principal catalysts for disulfide bond formation. Here, we investigated three rice (Oryza sativa) PDI family members (PDIL1;1, PDIL1;4, and PDIL2;3) and found that PDIL1;1 exhibited the highest catalytic activity for both disulfide bond formation and disulfide bond red...

BACKGROUND The aim of this study was to evaluate a novel oxidative stress marker (thiol/disulfide homeostasis) in attention deficit hyperactivity disorder (ADHD) children for the first time in literature. METHODS Ninety children with ADHD diagnosed according to DSM-V and as control group, 65 healthy children were included to the study. Native thiol, total thiol, disulfide, disulfide/native th...

   Surfaces of synthesis cobalt disulfide has high electron density that could interact with polycyclic aromatic compounds by π-π stacking. Cobalt disulfide was synthesized with the hydrothermal method and characterized by field emission scanning electron microscopy, X-ray diffraction and energy-dispersive X-ray. Using tetracycline as a model analyte, the batch adsorption experiments were c...

BACKGROUND Disulfide-linked oligodeoxyribonucleotide (ODN) liposomes were formulated and evaluated for the delivery of antisense ODN G3139 in KB human oral carcinoma cells. MATERIALS AND METHODS Liposomes composed of 1,2-di-(9Z-octadecenoyl)-3-trimethylammo-nium-propane (DOTAP)/egg phosphatidylcholine/alpha-tocopheryl polyethylene glycol 1000 succinate were incorporated with hydrophobized dis...

Objective: The main objective of this study was to compare the effects minimal and high gas flow-controlled hypotension applications on IMA thiol/disulfide balance, which are indicators oxidative stress.Methods: Patients undergoing elective tympanoplasty were randomized two groups as minimal-flow high-flow anesthesia groups. Minimal flow performed with 5L/min fresh reduced 0.4 L/min. High admin...

We report a detailed classification of disulfide patterns to further understand the role of disulfides in protein structure and function. The classification is applied to a unique searchable database of disulfide patterns derived from the SwissProt and Pfam databases. The disulfide database contains seven times the number of publicly available disulfide annotations. Each disulfide pattern in th...