BACKGROUND The activities of the Global Programme for the Elimination of Lymphatic Filariasis have been in operation since the year 2000, with Mass Drug Administration (MDA) undertaken yearly in disease endemic communities. Information collected during MDA-such as population demographics, age, sex, drugs used and remaining, and therapeutic and geographic coverage-can be used to assess the quali...

Kingpin axis geometry is crucial to the design of a suspension system. Suspension construction is truly three-dimensional, and the screw axis theory allows for a more accurate kinematic analysis. This study aims to present a dual quaternion analysis (DQA) method for calculating the kingpin axis geometry. The corresponding parameters include the caster angle, SAI angle, toe angle, caster trail a...

The MHC of cattle encodes two distinct isotypes of class II molecules, DR and DQ. Unlike humans, cattle lack the DP locus and about half the common haplotypes express duplicated DQ genes. The number and frequency of DQA and DQB alleles means that most cattle are heterozygous. If inter- and/or intrahaplotype pairing of DQA and DQB molecules occurs, cattle carrying DQ-duplicated haplotypes may ex...

BACKGROUND There are few published standards or methodological guidelines for integrating Data Quality Assurance (DQA) protocols into large-scale health systems research trials, especially in resource-limited settings. The BetterBirth Trial is a matched-pair, cluster-randomized controlled trial (RCT) of the BetterBirth Program, which seeks to improve quality of facility-based deliveries and red...

Family and population studies indicate that predisposition to insulin-dependent (type I) diabetes mellitus (IDDM) is polygenic. It has been shown that the absence of the aspartic acid in position 57 (Asp57) of the DQ/i chain is positively correlated to IDDM. However, Asp57-negative haplotypes do not always confer susceptibility and conversely, some Asp57-positive haplotypes seem to be disease a...

Analytical target cascading (ATC) is an effective decomposition approach used for engineering design optimization problems that have hierarchical structures. With ATC, the overall system is split into subsystems, which are solved separately and coordinated via target/response consistency constraints. As parallel computing becomes more common, it is desirable to have separable subproblems in ATC...

The major histocompatibility complex (MHC) is central to maintaining the immunologic vigor of individuals and populations. Classical MHC class II genes were targeted for partial sequencing in sea otters (Enhydra lutris) from populations in California, Washington, and Alaska. Sequences derived from sea otter peripheral blood leukocyte mRNAs were similar to those classified as DQA, DQB, DRA, and ...

Data quality assessments (DQA) are necessary to ensure valid research results. Despite the growing availability of tools relevance for DQA in R language, a systematic comparison their functionalities is missing. Therefore, we review packages related data (DQ) and assess scope against DQ framework observational health studies. Based on search, screened more than 140 Comprehensive Archive Network...

Southern hybridisation was used to define an apparent gene duplication event at the ovine DQA2 locus. Approximately 500 sheep from five different breeds were genotyped at their DQA1 and DQA2 loci. A subset of these were selected for further characterisation. Southern hybridisation of TaqI digested DNA revealed no DQA1 region in some sheep. It was also noted in these DQA1 null animals the DQA2 s...