Three simple spectrophotometric methods have been developed for simultaneous estimation of Drotaverine HCl and Omeprazole from tablet dosage form. Method-I involves, formation of Q-absorbance equation at 306.0 nm (isoabsorptive point) and 229.5 nm (lmax of drotaverine); simultaneous equation method (Method-II) and Method-III is the multicomponent mode of analysis in which the inbuilt software c...

OBJECTIVE To compare efficacy and tolerability of drotaverine 80 mg and ibuprofen 400 mg in patients with primary dysmenorrhoea. MATERIALS AND METHODS Nine-month, multicenter (11 study centers in Poland), randomised, double-blind, phase III study, conducted in two parallel group, included 345 women between the ages of 18 and 35, suffering from primary dysmenorrhoea with presence of moderate t...

Background: Dysfunctional labour is the commonest abnormality of first stage labour. It complicates 50% nulliparous deliveries and associated with increased perinatal morbidity mortality. occurs when progress in active phase abnormally slow (<1 cm/hr). largely due to ineffective uterine contractions or cervical dilatation. Augmentation oxytocin standard management dysfunctional as it enhance...

A sensitive, stability-indicating gradient RP-HPLC method with PDA detection has been developed for the simultaneous analysis of drotaverine impurities in active pharmaceutical ingredient (API) and pharmaceutical formulations. Efficient chromatographic separation was achieved on an XTerra RP18, 150 × 4.6 mm, 5 μm column using gradient elution at 230 nm detection wavelength. The optimized mobile...