objectives: anticonvulsant drugs can cause various forms of skin drug reactions, ranging from exanthema to severe blistering reactions. some studies have reported an association between hla-b*1502 allele and severe skin reactions. materials and methods: fifteen patients with severe skin reactions following treatment with anticonvulsant drugs (carbamazepine, lamotrigine, phenobarbital, primidone...

objectives the objective of this study was to develop the primers for single and/or multiplex pcr amplification assays for simultaneous identification of class a, class b, and class d carbapenem hydrolyzing β-lactamases in enterobacteriaceae and then to evaluate their efficiency. conclusions we have reported here a reliable method, composed of single and multiplex pcr assays, for screening all ...

background: adverse drug reactions (adrs) are one of the leading causes of morbidity and mortality and contribute to excessive health care costs. detection and reporting of adrs could decrease these consequences. the present study was designed to assess the knowledge, attitude and practice (kap) of pharmacy students towards adrs monitoring and reporting. methods: a questionnaire was prepared to...

This is a case report of an oral lichenoid drug reaction of the buccal sulci in a female diabetic patient who was on an anti-hypertensive drug, alpha-methyldopa (Aldomet) and an oral hypoglycaemic drug, chlorpropamide (Diabinese). The clinical features, histological findings and management are presented.

Background: Fixed drug eruption (FDE) is an uncommon adverse reaction to medications. Mucosal areas, particularly the male genitalia, are favored sites. To our knowledge, no study has investigated the causative agent(s) in FDE occurring on male genitals of Iranian patients. So, we conducted a study to determine the most common agents and areas of involvement in fixed genital drug eruption of ma...

Background: Cutaneous drug reaction seems to be relatively common The aim of the study was to recognize offending drugs, evaluate patients' characteristics and educate the patients to avoid selfadministration and re-administration of drugs. Methods: We retrospectively and prospectively analyzed data from Sina hospital in Tabriz (2000-2005) to determine the number of hospitalizations and visits ...