A 62-year-old woman with a history of CD for 13 years and hepatitis B virus infection was admitted because of general weakness, body weight loss (4 kg in 5 months), and pitting edema on the legs for 1 month. The patient had undergone previous surgeries for left leg fracture and a thyroid nodular goiter. A follow-up colonoscopy within 5 years before this admission demonstrated inflammation with ...