The paper byWalton et al. [13] in this issue of Pain brings a new perspective to the problem of central pain, in this case complex regional pain syndrome without peripheral nerve injury (CRPSI). It is a perspective that may have escaped the notice of many pain scientists and sensory physiologists. Walton et al. [13] using magnetoencephalography (MEG) compared brain activity in sufferers from ty...

Investigators at the National Hospital for Neurology and Neurosurgery, Queen Square, London, and multiple centers in the UK, Europe, US, Melbourne, Australia, and Canada, analyzed ECG recordings of 52 patients with alternating hemiplegia from 9 countries; all had whole-exome, whole-genome, or direct Sanger sequencing of ATP1A3; 47 had a confirmed missense mutation in ATP1A3.

Background. Recent studies examining mechanisms of defibrillation have focused on prolongation of graded cellular response duration during refractory period stimulation. This mechanism assumes that defibrillation shocks interact with ventricular cells during the process of repolarization. Methods and Results. To test this assumption, we examined monophasic action potentials (MAPs) from 171 epis...

This is the first reported case of a woman suffering a potentially fatal dysrhythmia and reinfarction during the same pregnancy and surviving to produce a healthy, live infant.

The scalar and intracardiac electrocardiograms recorded at the time of cardiac catheterization in 5 patients with ventricular pre-excitation have been analysed. Four patients had paroxysmal tachycardia on one or more occasions during the procedure. In each case where complete records were available the dysrhythmia was an atrial reciprocating tachycardia and this rhythm wasnoted at some time dur...