Induction of preneoplastic lesions, termed enzyme-altered foci (EAF), is considered to be an early step in the development of liver cancer. In view of the relatively homogenous properties of the majority of EAF, these lesions are suggested to arise as an adaptive response to toxic stress. An overall goal of this thesis was to study the role of adaptations to genotoxic stress in EAF development ...

The selective removal of lead and chlorine with minimizing zinc loss from electric arc furnace (EAF) dust is very important in the process for recovering high purity zinc from the EAF dust by high temperature metal recovery (HTMR) processes. In this study, the volatilization reaction of lead contained in the EAF dust was investigated at reaction temperatures between 973 and 1223K in air. The ma...

Background: Excessive production of oxygen free radicals and imbalance in the mechanisms responsible for antioxidant protection may result in the onset of many diseases including breast cancer. Objective: To evaluate antiproliferative and antioxidant activity of an ethylacetate fraction (EAF) of Picria fel-terrae Lour. Herbs in the T47D cell line. Methods: Phenolic and total flavonoid contents ...

The present study was designed to characterize the bone protective effects of (-)-epiafzelechin (EAF), a flavan-3-ol, in mature ovariectomized mice model and its ability to stimulate osteoblastic activity and inhibit osteoclastic activity. Mature C57BL/6 mice (three to four months old) were either ovariectomised (OVX) or sham-operated and subjected to treatment (vehicle, 17β-oestradiol (E2, 200...

The purpose of the study was to determine the relation between quintiles of muscular strength after adjustment for age and body weight, and excessive body fat (EBF) and excessive abdominal fat (EAF) when controlling for cardiorespiratory fitness (CRF) and other potential confounders. A two-phased cross-sectional and longitudinal study was conducted assessing the prevalence and incidence of EBF ...

This study was designed to investigate the antioxidant activity, hepatoprotective effect, and phenolic composition of the ethyl acetate fraction (EAF) extracted from Houttuynia cordata tea. EAF was shown to exhibit strong ferric-reducing antioxidant power (FRAP) and scavenging activity against DPPH radical in vitro, and the antioxidant effects were further verified by suppressing CCl4-induced o...

Antioxidant effects of ethyl acetate fraction of Mentha spicata (L.) were evaluated against 4-nitroquinoline-1-oxide injected mice. For this study, experiment setup consisted of 36 albino mice of either sex divided into 6 groups: Control (25% DMSO in water), ethyl acetate fraction (EAF) alone group (80, 160 mg/Kg body weight-bwt), 4-NQO (7.5 mg/Kg bwt-IP) alone and 4-NQO + EAF. EAF and vehicles...

This paper provides evidence that the leaves and stem of Passiflora serratodigitata L. dry crude extract (DCE), ethylacetate fraction (EAF), and residual water fraction show potential antiulcerogenic activity. Interestingly, the polymeric nanocapsule loaded with EAF had 10-fold more activity than the free EAF. Furthermore, the polymer nanoparticles provided homogeneous colloidal drug delivery s...

The complete nucleotide sequence was determined for pMAR7, an enteropathogenic Escherichia coli (EPEC) adherence factor (EAF) plasmid that contains genes encoding a type IV attachment pilus (Bfp) and the global virulence regulator per. Prototypic EAF plasmid pMAR7 is self-transmissible, unlike the smaller EAF plasmid pB171, which has no genes encoding conjugative functions. The tra locus, a hig...

With the increasing popularity of touch screen mobile devices, improving the usability and the user experience while inputting text on these devices is becoming increasingly important. Most conventional touch screen keyboards on mobile devices rely heavily on visual feedback, while auditory feedback seldom includes any useful information about what is being inputted by the user. The auditory fe...