Non-enzymatic glycation of proteins is the major cause of diabetic complications and therefore, inhibition of this reaction could reduce the morbidity of this disease. The aim of this study was to evaluate the in vitro effects of aqueous and hydroethanol extracts of Echium italicum L., Anchusa arvensis L. and Trichodesma incanum (Bunge) A. DC. of Boraginaceae on albumin, hemoglobin, and crystal...

The methanolic extract of the whole plant of Echium glomeratum Poir. (Boraginaceae) has afforded five pyrrolizidine alkaloids, three that were (7S, 8R)-petranine (1), (7S, 8S)-petranine (2), and (7R, 8R)-petranine (3a) or (7R, 8S)-petranine (3b), comprising a tricyclic pyrrolizidine alkaloids subclass; and two that were known but to the species: 7-angeloylretronecine (4) and 9-angeloylretroneci...

Pyrrolizidine alkaloids (PAs) in honey can be a potential human health risk. So far, it has remained unclear whether PAs in honey originate from pollen or floral nectar. We obtained honey, nectar, and plant pollen from two observation sites where Echium vulgare L. was naturally abundant. The PA concentration of honey was determined by targeted analysis using a high pressure liquid chromatograph...

Background & Aims: Echium amoenum and Citrus aurantifolia are used in traditional medicine for the treatment of cardiac arrhythmia and regulation of blood pressure. In this study the effects of coadministration of these herbs on heart rate and blood pressure of rats before and after phynelephrine injection were investigated. Methods: Ten groups of rats respectively received 100, 200, 400 an...

Echium amoenum belong to Boraginaceae family is a biennial or perennial herb indigenous to the narrow zone of northern part of Iran and Caucasus.the aim of this study was to overview the therapeutic effects of Iranian borage (Echium amoenum Fisch).This review article was carried out by searching studies in PubMed, Medline, Web of Science, and Iran Medex databases .The initial search strategy id...

soil salinity affects ions concentrationss of plant tissues and this may alter the merits quality of medicinal plants. experiments were conducted during 2003 at the the isfahan university of technology campus, isfahan, iran, to assess the effects of five soil salinity levels (3.2, 3.6, 4.5, 5.4 and 7.5 ds m-1) on na, k, and ca contents of borage and echium. each plant species was studied in a s...

OBJECTIVE Echium amoenum Fisch. & C.A. Mey. is used for the treatment of various diseases in traditional medicine. This plant is a major source of anthocyanins with beneficial cardiovascular properties such as anti-atherosclerotic and antihypertensive effects. In the present study, the protective and antioxidant effects of anthocyanin-rich E. amoenum extract were evaluated on human vascular end...

UNLABELLED Botanical seed oils reduce the generation of leukotrienes in patients with asthma. Our objective was to determine the efficacy of a botanical seed oil combination against airflow obstruction in asthma, and to determine the pharmacogenomic effect of the leukotriene C4 synthase (LTC4S) polymorphism A-444C. We conducted a randomized, double-blind, placebo-controlled, cross-over clinical...