Tomm40 has created a stir in Alzheimer’s disease (AD) research with the recent proposal that variablelength polymorphisms of this gene, which lives near apolipoprotein E (ApoE) on chromosome 19, can help predict at what age a person may develop late-onset AD (LOAD) [1,2]. This finding came from analysis of several small cohorts in which ages of LOAD onset were determined retrospectively. Now, n...