OBJECTIVE To analyse the value of the INTERMED, a screening instrument to assess case complexity, compared with the Expanded Disability Status Scale (EDSS) and the Guy's Neurological Disability Scale (GNDS) to identify multiple sclerosis (MS) patients in need of multidisciplinary treatment. METHODS One hundred MS patients underwent INTERMED, EDSS, and GNDS examinations. Patient care needs wer...

Watershed management, in its very nature, represents a participatory process, requiring horizontal and vertical collaborations among multiple institutions and stakeholders. For watershed-scale management to be effective, a social-learning infrastructure needs to be in place to allow for the integration of diverse knowledge and interests related to watershed protection and restoration. Environme...

Among other symptoms, multiple sclerosis can also produce symptoms of affective and cognitive disorders. The majority of patients have certain cognitive dysfunctions, and the' most common affective disorder is reactive depression. The aim of the study was to determine the correlation of the Mini-Mental State (MMS) and Beck Depression Inventory (BDI) scale scores with the Expanded Disability Sta...

OBJECTIVE To prospectively characterize the relation between 1-year changes in neurologist ratings of abnormalities as measured by means of the Expanded Disability Status Scale (EDSS) and changes in observations of functional impairment as measured by means of the Multiple Sclerosis Functional Composite (MSFC) in the clinical assessment of multiple sclerosis (MS). METHODS One hundred twenty p...

[Purpose] To investigate the relationship between isokinetic knee muscle strength and kinematic, kinetic and spatiotemporal gait parameters of patients with multiple sclerosis (MS). [Subjects and Methods] Twenty-nine MS patients (mean age 31.5±6.5) were investigated in this study. The isokinetic knee muscle strength and gait parameters of MS patients with moderate and severe disability, as dete...

An environmental decision support system (EDSS) can be used as an important tool for the rehabilitation and preservation of ecosystems. Nonetheless, high assimilation costs (both money time) are one main reasons these tools not widely adopted in practice. This work presents a low-cost paradigm “EDSS Service.” is demonstrated developing water quality EDSS service that utilizes well-known CE-QUAL...

OBJECTIVES Recent phase III clinical trials of immunomodulatory therapies in relapsing-remitting multiple sclerosis have shown significant benefits of active treatment on relapse related end points, but effects on disability outcomes have been inconsistent. These apparent discrepancies could be due to differences in the clinical end points employed, the behaviour of placebo cohorts, or both. ...

BACKGROUND There are a number of instruments that describe severity and progression of multiple sclerosis and they are increasingly used as endpoints to assess the effectiveness of therapeutic interventions. We examined to what extent the psychometric properties of two accepted instruments--EDSS and MSFC--meet methodological standards and the value they have in clinical trials. METHODS We con...

Disability status, depression and anxiety are important determinants of quality of life (QoL) in patients with multiple sclerosis (MS). We investigated whether anxiety and depression influence the relation between disability status and QoL in our cohort of recently diagnosed patients. Disability status [Expanded Disability Status Scale (EDSS)], anxiety and depression [Hospital Anxiety and Depre...

The problem of estimating the parameters of exponentially damped sinusoids (EDSs) signal has received very much attention in many fields. In this paper, a specific neural network termed EDSNN for parameter estimation of the EDSs has been proposed. Aiming at effectively evaluating the parameters of the EDSs signal, we construct a specific topology of EDSNN strictly following the mathematic formu...